|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0020964,
umls-concept:C0041361,
umls-concept:C0087111,
umls-concept:C0175671,
umls-concept:C0205263,
umls-concept:C0298987,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
|
|
pubmed:issue |
12
|
|
pubmed:dateCreated |
2005-6-16
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|
pubmed:abstractText |
The carcinogen activator cytochrome P450 1B1 (CYP1B1) is expressed on almost all human tumors with rare expression on normal tissues. Anti-CYP1B1-specific T cells kill CYP1B1-expressing tumors, providing the rationale to examine CYP1B1 as a target for immunotherapy.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
1078-0432
|
|
pubmed:author |
pubmed-author:BeachKathleenK,
pubmed-author:BoyajianRichardR,
pubmed-author:CamposSusanaS,
pubmed-author:GilliganTimothy DTD,
pubmed-author:GribbenJohn GJG,
pubmed-author:HedleyMary LML,
pubmed-author:MarshallBlossomB,
pubmed-author:MatulonisUrsulaU,
pubmed-author:NadlerLee MLM,
pubmed-author:NealonPatrickP,
pubmed-author:NeubergDonnaD,
pubmed-author:RichardsonPaul GPG,
pubmed-author:RyanDavid PDP,
pubmed-author:UrbanRobert GRG
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
11
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
4430-6
|
|
pubmed:dateRevised |
2006-5-1
|
|
pubmed:meshHeading |
pubmed-meshheading:15958627-Aged,
pubmed-meshheading:15958627-Antigens, Neoplasm,
pubmed-meshheading:15958627-Aryl Hydrocarbon Hydroxylases,
pubmed-meshheading:15958627-Cancer Vaccines,
pubmed-meshheading:15958627-Feasibility Studies,
pubmed-meshheading:15958627-Female,
pubmed-meshheading:15958627-Humans,
pubmed-meshheading:15958627-Immunotherapy,
pubmed-meshheading:15958627-Male,
pubmed-meshheading:15958627-Middle Aged,
pubmed-meshheading:15958627-Neoplasms,
pubmed-meshheading:15958627-Plasmids,
pubmed-meshheading:15958627-Time Factors,
pubmed-meshheading:15958627-Treatment Outcome
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
Unexpected association between induction of immunity to the universal tumor antigen CYP1B1 and response to next therapy.
|
|
pubmed:affiliation |
Department of Medical Oncology, Dana-Farber Cancer Institute and Division of Medical Oncology, Brigham and Women's Hospital, Boston, MA 02115, USA.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Clinical Trial, Phase I
|
