Source:http://linkedlifedata.com/resource/pubmed/id/15957196
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
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| pubmed:dateCreated |
2005-6-14
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| pubmed:abstractText |
Confirmatory factor analysis was used to examine a proposed factor structure of a comprehensive neuropsychological battery used to study patients with schizophrenia and related psychotic disorders (n = 209). An a priori six-factor model and five nested models were evaluated successively, using maximum likelihood confirmatory factor analysis. In all multifactor models, the factors were significantly intercorrelated. A six-factor model with two pairs of correlated errors fit the neuropsychological data significantly better than competing models with fewer factors. The six factors included verbal crystallized, attention/working memory, verbal episodic memory, speed of information processing, visual episodic memory, and reasoning/problem solving. Severity of negative symptoms was significantly associated with worse performance on attention/working memory and verbal crystallized factors, but positive symptoms, depression, and a summary measure of psychopathology were not significantly related to neuropsychological performance. Impairment on a performance-based measure of functional capacity was significantly related to all neuropsychological factors. A simultaneous confirmatory factor analysis using the original sample and a group of healthy subjects (n = 131) demonstrated that the six-factor model of cognition was generalizable and applied equally well to both groups.
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| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0586-7614
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
30
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
739-54
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| pubmed:dateRevised |
2007-11-14
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| pubmed:meshHeading |
pubmed-meshheading:15957196-Adolescent,
pubmed-meshheading:15957196-Adult,
pubmed-meshheading:15957196-Aged,
pubmed-meshheading:15957196-Aged, 80 and over,
pubmed-meshheading:15957196-Antipsychotic Agents,
pubmed-meshheading:15957196-Brief Psychiatric Rating Scale,
pubmed-meshheading:15957196-Cognition Disorders,
pubmed-meshheading:15957196-Diagnostic and Statistical Manual of Mental Disorders,
pubmed-meshheading:15957196-Factor Analysis, Statistical,
pubmed-meshheading:15957196-Female,
pubmed-meshheading:15957196-Hospitalization,
pubmed-meshheading:15957196-Humans,
pubmed-meshheading:15957196-Length of Stay,
pubmed-meshheading:15957196-Male,
pubmed-meshheading:15957196-Middle Aged,
pubmed-meshheading:15957196-Neuropsychological Tests,
pubmed-meshheading:15957196-Psychotic Disorders,
pubmed-meshheading:15957196-Schizophrenia,
pubmed-meshheading:15957196-Severity of Illness Index
|
| pubmed:year |
2004
|
| pubmed:articleTitle |
A six-factor model of cognition in schizophrenia and related psychotic disorders: relationships with clinical symptoms and functional capacity.
|
| pubmed:affiliation |
Department of Psychiatry, University of California, San Diego 92161, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
|