|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2005-7-11
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|
pubmed:abstractText |
Tramadol is potentially a very useful pain relief medication in neonates and infants. It is primarily metabolized into O-demethyl tramadol (M1) by CYP2D6. Data concerning tramadol disposition and CYP2D6 activity in young infants are not available.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0007-0912
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
95
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
231-9
|
|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:15951326-Adult,
pubmed-meshheading:15951326-Analgesics, Opioid,
pubmed-meshheading:15951326-Cytochrome P-450 CYP2D6,
pubmed-meshheading:15951326-Dose-Response Relationship, Drug,
pubmed-meshheading:15951326-Humans,
pubmed-meshheading:15951326-Infant,
pubmed-meshheading:15951326-Infant, Newborn,
pubmed-meshheading:15951326-Linear Models,
pubmed-meshheading:15951326-Middle Aged,
pubmed-meshheading:15951326-Time Factors,
pubmed-meshheading:15951326-Tramadol
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|
pubmed:year |
2005
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|
pubmed:articleTitle |
Tramadol disposition in the very young: an attempt to assess in vivo cytochrome P-450 2D6 activity.
|
|
pubmed:affiliation |
Neonatal Intensive Care Unit, Department of Paediatrics, University Hospital, Gasthuisberg, Leuven, Belgium. karel.allegaert@uz.kuleuven.ac.be
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|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
|
