|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0009566,
umls-concept:C0019080,
umls-concept:C0030705,
umls-concept:C0035696,
umls-concept:C0040028,
umls-concept:C0087086,
umls-concept:C0218227,
umls-concept:C0441889,
umls-concept:C1171362,
umls-concept:C1257890,
umls-concept:C1704788
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2005-6-13
|
|
pubmed:abstractText |
C-Mpl and PRV-1 expression was measured in a cohort of 48 patients with essential thrombocythemia (ET). A retrospective analysis was conducted to asses whether the presence of one or both markers correlates with a higher risk of developing thromboembolic complications. In this cohort, PRV-1 overexpression was associated with a significantly increased risk of thrombosis, whereas decreased c-Mpl expression was not. The results of this retrospective analysis must now be corroborated in a large, prospective trial of newly diagnosed patients.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CD177 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/GPI-Linked Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Isoantigens,
http://linkedlifedata.com/resource/pubmed/chemical/MPL protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cytokine,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Thrombopoietin
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
1592-8721
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
90
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
851-3
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:15951300-Adult,
pubmed-meshheading:15951300-Aged,
pubmed-meshheading:15951300-Aged, 80 and over,
pubmed-meshheading:15951300-Female,
pubmed-meshheading:15951300-GPI-Linked Proteins,
pubmed-meshheading:15951300-Hemorrhage,
pubmed-meshheading:15951300-Humans,
pubmed-meshheading:15951300-Isoantigens,
pubmed-meshheading:15951300-Male,
pubmed-meshheading:15951300-Membrane Glycoproteins,
pubmed-meshheading:15951300-Middle Aged,
pubmed-meshheading:15951300-Proto-Oncogene Proteins,
pubmed-meshheading:15951300-RNA, Messenger,
pubmed-meshheading:15951300-Receptors, Cell Surface,
pubmed-meshheading:15951300-Receptors, Cytokine,
pubmed-meshheading:15951300-Receptors, Thrombopoietin,
pubmed-meshheading:15951300-Retrospective Studies,
pubmed-meshheading:15951300-Risk,
pubmed-meshheading:15951300-Thrombocythemia, Essential,
pubmed-meshheading:15951300-Thrombosis
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
Thrombotic and bleeding complications in four subpopulations of patients with essential thrombocythemia defined by c-Mpl protein expression and PRV-1 mRNA levels.
|
|
pubmed:publicationType |
Letter,
Research Support, Non-U.S. Gov't
|
