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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2005-6-10
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pubmed:abstractText |
Thymus and activation-regulated chemokine (TARC; CCL17) is a lymphocyte-directed CC chemokine that specifically attracts T-helper (Th) 2 cells positive for the CC chemokine receptor 4 (CCR4(+)). Corticosteroids reduce airway inflammation, as reflected by reduced numbers of eosinophils and T cells and reduced expression of cytokines. We investigated TARC production and the inhibitory effects of corticosteroids on TARC expression in a murine model of allergic asthma.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adrenal Cortex Hormones,
http://linkedlifedata.com/resource/pubmed/chemical/Ccl17 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Ccr4 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL17,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines, CC,
http://linkedlifedata.com/resource/pubmed/chemical/Cxcr3 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Dexamethasone,
http://linkedlifedata.com/resource/pubmed/chemical/Methacholine Chloride,
http://linkedlifedata.com/resource/pubmed/chemical/Ovalbumin,
http://linkedlifedata.com/resource/pubmed/chemical/RNA,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CCR4,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CXCR3,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Chemokine
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pubmed:status |
MEDLINE
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pubmed:issn |
1018-2438
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pubmed:author |
pubmed-author:AdachiMitsuruM,
pubmed-author:AkabaneTomokoT,
pubmed-author:AsanoKazuhitoK,
pubmed-author:HonmaIkuoI,
pubmed-author:IekiKoushiK,
pubmed-author:IwaseMichikoM,
pubmed-author:KawaguchiMioM,
pubmed-author:KokubuFumioF,
pubmed-author:KurokawaMasatsuguM,
pubmed-author:MatsukuraSatoshiS,
pubmed-author:OdakaMihoM,
pubmed-author:SuzukiShintarouS,
pubmed-author:TakeuchiHirokoH,
pubmed-author:WatanabeShinS
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pubmed:copyrightInfo |
Copyright 2005 S. Karger AG, Basel.
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pubmed:issnType |
Print
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pubmed:volume |
137 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
60-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15947487-Adrenal Cortex Hormones,
pubmed-meshheading:15947487-Animals,
pubmed-meshheading:15947487-Asthma,
pubmed-meshheading:15947487-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:15947487-Cell Count,
pubmed-meshheading:15947487-Chemokine CCL17,
pubmed-meshheading:15947487-Chemokines, CC,
pubmed-meshheading:15947487-Dexamethasone,
pubmed-meshheading:15947487-Disease Models, Animal,
pubmed-meshheading:15947487-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:15947487-Immunohistochemistry,
pubmed-meshheading:15947487-Lung,
pubmed-meshheading:15947487-Male,
pubmed-meshheading:15947487-Methacholine Chloride,
pubmed-meshheading:15947487-Mice,
pubmed-meshheading:15947487-Mice, Inbred BALB C,
pubmed-meshheading:15947487-Ovalbumin,
pubmed-meshheading:15947487-RNA,
pubmed-meshheading:15947487-Receptors, CCR4,
pubmed-meshheading:15947487-Receptors, CXCR3,
pubmed-meshheading:15947487-Receptors, Chemokine,
pubmed-meshheading:15947487-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2005
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pubmed:articleTitle |
Effects of corticosteroid on the expression of thymus and activation-regulated chemokine in a murine model of allergic asthma.
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pubmed:affiliation |
First Department of Internal Medicine, Showa University School of Medicine, Tokyo, Japan.
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pubmed:publicationType |
Journal Article
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