| pubmed-article:15942942 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15942942 | lifeskim:mentions | umls-concept:C1335193 | lld:lifeskim |
| pubmed-article:15942942 | lifeskim:mentions | umls-concept:C0243095 | lld:lifeskim |
| pubmed-article:15942942 | lifeskim:mentions | umls-concept:C0034897 | lld:lifeskim |
| pubmed-article:15942942 | lifeskim:mentions | umls-concept:C1550594 | lld:lifeskim |
| pubmed-article:15942942 | lifeskim:mentions | umls-concept:C1516520 | lld:lifeskim |
| pubmed-article:15942942 | lifeskim:mentions | umls-concept:C0017351 | lld:lifeskim |
| pubmed-article:15942942 | lifeskim:mentions | umls-concept:C0439855 | lld:lifeskim |
| pubmed-article:15942942 | lifeskim:mentions | umls-concept:C1511695 | lld:lifeskim |
| pubmed-article:15942942 | lifeskim:mentions | umls-concept:C1548760 | lld:lifeskim |
| pubmed-article:15942942 | lifeskim:mentions | umls-concept:C1547300 | lld:lifeskim |
| pubmed-article:15942942 | lifeskim:mentions | umls-concept:C1515021 | lld:lifeskim |
| pubmed-article:15942942 | lifeskim:mentions | umls-concept:C0580822 | lld:lifeskim |
| pubmed-article:15942942 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:15942942 | pubmed:dateCreated | 2005-8-8 | lld:pubmed |
| pubmed-article:15942942 | pubmed:abstractText | We present an extensive characterization of 10 B-cell lymphomas with a t(9;14)(p13;q32). The presence of the PAX5/IGH gene rearrangement was demonstrated by fluorescence in situ hybridization (FISH) using a validated probe set, whereas complex karyotypic changes were reassessed by multiplex-FISH (M-FISH). Pathologic and clinical review revealed the presence of this rearrangement in 4 histiocyte-rich, T-cell-rich B-cell lymphomas (HRTR-BCLs) and 2 posttransplantation diffuse large B-cell lymphomas (PTLD-DLBCLs). In contrast to initial observations describing this translocation in lymphoplasmacytic lymphoma (LPL) and LPL-derived large B-cell lymphoma, our data showed a wide morphologic and clinical spectrum associated with the PAX5/IGH rearrangement, pointing to an association between this aberration and a subset of de novo DLBCLs presenting with advanced disease and adverse prognosis. In addition, the recurrent incidence of this rearrangement in both HRTR-BCL (4 cases) and PTLD-DLBCL (2 cases) was previously unrecognized and is intriguing. | lld:pubmed |
| pubmed-article:15942942 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15942942 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15942942 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15942942 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15942942 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15942942 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15942942 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15942942 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15942942 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15942942 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:15942942 | pubmed:issn | 1045-2257 | lld:pubmed |
| pubmed-article:15942942 | pubmed:author | pubmed-author:DastugueNicol... | lld:pubmed |
| pubmed-article:15942942 | pubmed:author | pubmed-author:Van... | lld:pubmed |
| pubmed-article:15942942 | pubmed:author | pubmed-author:PoppeBruceB | lld:pubmed |
| pubmed-article:15942942 | pubmed:author | pubmed-author:MichauxLucien... | lld:pubmed |
| pubmed-article:15942942 | pubmed:author | pubmed-author:HerensChristi... | lld:pubmed |
| pubmed-article:15942942 | pubmed:author | pubmed-author:De PaepeAnneA | lld:pubmed |
| pubmed-article:15942942 | pubmed:author | pubmed-author:SpelemanFrank... | lld:pubmed |
| pubmed-article:15942942 | pubmed:author | pubmed-author:De... | lld:pubmed |
| pubmed-article:15942942 | pubmed:author | pubmed-author:CavazziniFran... | lld:pubmed |
| pubmed-article:15942942 | pubmed:author | pubmed-author:WlodarskaIwon... | lld:pubmed |
| pubmed-article:15942942 | pubmed:author | pubmed-author:De... | lld:pubmed |
| pubmed-article:15942942 | pubmed:author | pubmed-author:PraetMarleenM | lld:pubmed |
| pubmed-article:15942942 | pubmed:author | pubmed-author:BastardChrist... | lld:pubmed |
| pubmed-article:15942942 | pubmed:author | pubmed-author:YigitNurtenN | lld:pubmed |
| pubmed-article:15942942 | pubmed:author | pubmed-author:MoreauElsE | lld:pubmed |
| pubmed-article:15942942 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15942942 | pubmed:volume | 44 | lld:pubmed |
| pubmed-article:15942942 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15942942 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15942942 | pubmed:pagination | 218-23 | lld:pubmed |
| pubmed-article:15942942 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:15942942 | pubmed:meshHeading | pubmed-meshheading:15942942... | lld:pubmed |
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| pubmed-article:15942942 | pubmed:meshHeading | pubmed-meshheading:15942942... | lld:pubmed |
| pubmed-article:15942942 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15942942 | pubmed:articleTitle | PAX5/IGH rearrangement is a recurrent finding in a subset of aggressive B-NHL with complex chromosomal rearrangements. | lld:pubmed |
| pubmed-article:15942942 | pubmed:affiliation | Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium. | lld:pubmed |
| pubmed-article:15942942 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15942942 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15942942 | lld:pubmed |
