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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2005-6-8
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pubmed:abstractText |
Newborn screening based on measurement of 17alpha-hydroxyprogesterone (17-OHP) in a dried blood spot on filter paper is an effective tool for early diagnosis of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. Its most important rationale is prevention of a life-threatening salt-wasting (SW) crisis; in moderate forms of CAH, early diagnosis and treatment may prevent permanent negative effects of androgen overproduction. Our target was to analyse if all CAH patients who had been identified clinically before puberty would have been detected by the newborn screening.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0804-4643
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pubmed:author |
pubmed-author:BattelinoTadejT,
pubmed-author:Baumgartner-ParzerSabina MSM,
pubmed-author:FrischHerwigH,
pubmed-author:KovácsJózsefJ,
pubmed-author:LakeR IRI,
pubmed-author:MöslingerDorotheaD,
pubmed-author:Middle European Society for Paediatric Endocrinology -- Congenital...,
pubmed-author:PribilincováZuzanaZ,
pubmed-author:SólyomJánosJ,
pubmed-author:TörökDóraD,
pubmed-author:VotavaFelixF,
pubmed-author:WaldhauserFranzF
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pubmed:issnType |
Print
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pubmed:volume |
152
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
869-74
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15941926-17-alpha-Hydroxyprogesterone,
pubmed-meshheading:15941926-Adrenal Hyperplasia, Congenital,
pubmed-meshheading:15941926-False Negative Reactions,
pubmed-meshheading:15941926-Female,
pubmed-meshheading:15941926-Humans,
pubmed-meshheading:15941926-Infant, Newborn,
pubmed-meshheading:15941926-Male,
pubmed-meshheading:15941926-Mass Screening,
pubmed-meshheading:15941926-Retrospective Studies
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pubmed:year |
2005
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pubmed:articleTitle |
Estimation of the false-negative rate in newborn screening for congenital adrenal hyperplasia.
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pubmed:affiliation |
Department of Paediatrics, Medical University of Vienna, Vienna, Austria.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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