Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
122
pubmed:dateCreated
2005-6-8
pubmed:abstractText
In 1998, WHO-IPCS re-assessed the TDI of dioxin, which was derived from the body burdens of TCDD exposed to the experimental animals. Then, the international assessment agencies and governmental assessment agencies have conducted the dioxin fs health assessment using the similar method to the WHO-IPCS approach. The key endpoints were reproductive and developmental toxicity caused by in utero and lactational exposure. Each assessment agencies used the similar data set of the toxicity studies, however, there are some differences about the TDI derivation method and the selection of adverse endpoints. This report reviewed the recent reproductive and developmental toxicity studies of the dioxins and summarized the health assessment in the international or governmental agencies, and discussed the appropriate TDI derivation.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1343-4292
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
56-61
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
[Recent TDI derivation of dioxin based on the reproductive and developmental toxicity].
pubmed:affiliation
Division of Risk Assessment.
pubmed:publicationType
Journal Article, English Abstract, Review