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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
2005-6-6
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pubmed:abstractText |
The majority of the lipoprotein in cerebrospinal fluid (CSF) is apolipoprotein E (apoE)-containing HDL. Since neuronal cells express lipoprotein receptors which recognize apoE, apoE in CSF-HDL is believed to be important for the development of central nervous system (CNS) in children. In adults, the apoE phenotype affects the plasma apoE concentration and the epsilon 4 allele is a risk factor for Alzheimer's disease. Due to the requirement for CNS development, we examined whether the apoE phenotype affects the composition and concentration of CSF-HDL in children.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0009-8981
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
356
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
110-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15936307-Adolescent,
pubmed-meshheading:15936307-Adult,
pubmed-meshheading:15936307-Age Factors,
pubmed-meshheading:15936307-Aged,
pubmed-meshheading:15936307-Aged, 80 and over,
pubmed-meshheading:15936307-Alzheimer Disease,
pubmed-meshheading:15936307-Apolipoprotein E4,
pubmed-meshheading:15936307-Apolipoproteins E,
pubmed-meshheading:15936307-Child,
pubmed-meshheading:15936307-Child, Preschool,
pubmed-meshheading:15936307-Cholesterol,
pubmed-meshheading:15936307-Female,
pubmed-meshheading:15936307-Humans,
pubmed-meshheading:15936307-Infant,
pubmed-meshheading:15936307-Lipoproteins, HDL,
pubmed-meshheading:15936307-Male,
pubmed-meshheading:15936307-Middle Aged,
pubmed-meshheading:15936307-Phenotype,
pubmed-meshheading:15936307-Phospholipids
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pubmed:year |
2005
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pubmed:articleTitle |
Effect of apolipoprotein E (apoE) phenotype on the apoE content of CSF-HDL in children.
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pubmed:affiliation |
Division of Endocrinology and Metabolism, Department of Homeostatic Regulation and Developments, Niigata University Graduate School of Medical and Dental Sciences, Asahimachi 1-757, Niigata City, Niigata 951-8510, Japan.
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pubmed:publicationType |
Journal Article
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