Source:http://linkedlifedata.com/resource/pubmed/id/15935982
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
2005-6-6
|
pubmed:abstractText |
Depot formulations of somatostatin analogues are increasingly used in the treatment of active acromegaly. A priori knowledge of the efficacy of these drugs in controlling GH excess is clinically relevant, because only approximately 60% of the patients respond with adequate control of GH (GH levels < 5 mU/L) and/or IGF-1 levels upon this treatment. Therefore, we assessed the acute responses of serum GH levels to a new octreotide test (intravenous administration of 50 microg) in 98 consecutive patients with active acromegaly and we measured the predictive value of this test for the efficacy of chronic octreotide-long acting repeatable (octreotide-LAR) treatment in 18 patients.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
1096-6374
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
200-6
|
pubmed:meshHeading |
pubmed-meshheading:15935982-Acromegaly,
pubmed-meshheading:15935982-Adult,
pubmed-meshheading:15935982-Aged,
pubmed-meshheading:15935982-Biological Availability,
pubmed-meshheading:15935982-Female,
pubmed-meshheading:15935982-Human Growth Hormone,
pubmed-meshheading:15935982-Humans,
pubmed-meshheading:15935982-Injections, Intravenous,
pubmed-meshheading:15935982-Male,
pubmed-meshheading:15935982-Middle Aged,
pubmed-meshheading:15935982-Octreotide,
pubmed-meshheading:15935982-Pituitary Function Tests,
pubmed-meshheading:15935982-Prognosis,
pubmed-meshheading:15935982-Treatment Outcome
|
pubmed:year |
2005
|
pubmed:articleTitle |
Intravenous octreotide test predicts the long term outcome of treatment with octreotide-long-acting repeatable in active acromegaly.
|
pubmed:affiliation |
Department of Metabolism and Endocrinology, Leiden University Medical Centre, P.O. Box 9600, 2300 RC, Leiden, The Netherlands. nrbiermasz@lumc.nl
|
pubmed:publicationType |
Journal Article,
Clinical Trial
|