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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2005-6-6
pubmed:abstractText
The present paper describes neuropeptide Y-like-immunoreactive (NPY-ir) structures in the brain of the spotted gar, Lepisosteus oculatus, with special regard to their anatomical relations to gonadotropin-releasing hormone (GnRH)-ir structures in the hypothalamus and the terminal nerve (TN). NPY-ir cells were found in various locations including the TN, the medial zone of the area dorsalis telencephali, the ventral nucleus of the area ventralis telencephali, the habenula, the dorsal posterior nucleus, the periventricular nucleus of the hypothalamus, the posterior tubercle, the optic tectum, and the lateral part of the tegmentum. NPY-ir fibers were widely distributed throughout the brain except for the cerebellum. They were locally dense in the ventral telencephalon, in the periventricular gray matter of the thalamus and the hypothalamus, and in the ventromedial part of the brainstem, but sparse in the olfactory system. Light-microscopic double immunohistochemistry demonstrated distinct NPY-ir and GnRH-ir structures in the ventral hypothalamus: the NPY-ir system was associated mainly with the periventricular gray matter, whereas the GnRH-ir system was prominent in the external zone of the preoptico-tubero-infundibular area including the median eminence (ME). Here, NPY-ir varicose fibers occasionally abutted on GnRH-ir cells and varicosities or invested GnRH-ir cells, suggesting that NPY directly regulates the function of the hypothalamic GnRHergic neuron system. On the other hand, the TN cells and fibers in the olfactory system were doubly labeled by the antibodies against NPY and GnRH. Immuno-electron-microscopic data strongly suggested that some of the TN fibers projected to the ME.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0016-6480
pubmed:author
pubmed:issnType
Print
pubmed:volume
142
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
336-46
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Neuropeptide Y-immunoreactive (NPY-ir) structures in the brain of the gar Lepisosteus oculatus (Lepisosteiformes, Osteichthyes) with special regard to their anatomical relations to gonadotropin-releasing hormone (GnRH)-ir structures in the hypothalamus and the terminal nerve.
pubmed:affiliation
Department of Biology, Nippon Dental University School of Dentistry at Niigata, Japan. chiba@ngt.ndu.ac.jp
pubmed:publicationType
Journal Article