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pubmed-article:15930366pubmed:abstractTextTreatment of hepatocellular carcinoma raised on cirrhotic liver represents a major endeavor because surgery and chemotherapeutic management fail to improve the clinical course of the disease. Chemoprevention could represent an important means to inhibit the process of hepatocarcinogenesis. Farnesyltransferase inhibitors are a class of drugs blocking the growth of tumor cells with minimal toxicity towards normal cells.lld:pubmed
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pubmed-article:15930366pubmed:articleTitleFarnesyltransferase inhibitor, ABT-100, is a potent liver cancer chemopreventive agent.lld:pubmed
pubmed-article:15930366pubmed:affiliationDipartimento di Medicina Interna, Università di Firenze, Florence, Italy. v.carloni@dmi.unifi.itlld:pubmed
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