To assess (i) the efficacy of short-term proton pump inhibitors (PPIs) in non-cardiac chest pain (NCCP) and (ii) the performance of an empirical short-term treatment with PPI (PPI test) to establish a diagnosis of abnormal acid reflux in NCCP.
Clinical Enteric Neuroscience, Translational and Epidemiological Research Program (C.E.N.T.E.R.) and Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.
