Linked Life Data

15927189

Source:http://linkedlifedata.com/resource/pubmed/id/15927189

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-1-27
pubmed:abstractText
Cartilage deformation demonstrates viscoelastic behavior due to its unique structure. However, nearly all contact studies investigating incongruity-associated changes in cartilage surface stresses have been static tests. These tests have consistently measured only modest increases in contact stresses, even with large incongruities. In this study, an experimental approach measuring real-time contact stresses in human cadaveric ankles during quasi-physiologic motion and loading was used to determine how stepoff incongruities of the distal tibia affected contact stresses and contact stress gradients. Peak instantaneous contact stresses, in ankles with stepoffs between 1.0 and 4.0mm of the anterolateral articular surface, increased by between 2.3 x and 3.0 x compared to the corresponding intact ankle values. Peak instantaneous contact stress gradients in stepoff configurations increased by between 1.9 x and 2.6 x the corresponding intact configuration values. Anatomic reduction of the displaced fragment restored intact contact stresses and contact stress gradients. Intact and anatomic configurations demonstrated a heterogeneous population of low-magnitude, randomly oriented contact stress gradient vectors in contrast to high-magnitude, preferentially oriented gradients in stepoff configurations. Peak instantaneous contact stresses may be important pathomechanical determinants of post-traumatic arthritis. Abnormal contact stress gradients could cause regional pathological disturbances in cartilage stress and interstitial fluid distribution. Measuring contact stresses and contact stress gradients during motion allowed potential incongruity-associated pathologic changes in loading that occur over the complete motion cycle to be investigated.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0021-9290
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
617-26
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Contact stress transients during functional loading of ankle stepoff incongruities.
pubmed:affiliation
Department of Orthopaedic Surgery, University of Iowa Hospitals and Clinics, 01021 JPP, 200 Hawkins Drive, Iowa City, IA 52242, USA. todd-mckinley@uiowa.edu
pubmed:publicationType
Journal Article, In Vitro, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural