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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1992-7-2
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pubmed:abstractText |
AB3217-A, a novel anti-mite substance, was isolated from the fermentation broth of a streptomycete strain. The strain was isolated from a soil collected at Kita-azumi, Nagano Prefecture, Japan, and identified as Streptomyces platensis AB3217. AB3217-A was purified by Amberlite IR120B, Diaion HP-20 and CM-Sephadex C-25 column chromatographies. The molecular formula was determined as C17H23NO7 by elemental analysis, MS and 13C NMR spectroscopy. The structure of AB3217-A was determined to be (1R,3S,4S,7R,8R,11R,12S,13R)-4,12,13-trihydroxy-8-(4-methoxy phenyl)-6-aza-2,9,14-trioxatricyclo-[9.2.1.0(3,7)]tetradecane by spectroscopic analysis and X-ray crystallographic analysis. The molecule of AB3217-A has unique structure that deacetylanisomycin and beta-D-xylofuranose linked through glycosidic bond and ether bond resulting in the formation of nine-membered ring. AB3217-A showed marked activity against the two spotted spider mite, Tetranychus urticae.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0021-8820
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
458-64
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1592678-Animals,
pubmed-meshheading:1592678-Aza Compounds,
pubmed-meshheading:1592678-Chromatography, Gel,
pubmed-meshheading:1592678-Crystallography,
pubmed-meshheading:1592678-Ethers,
pubmed-meshheading:1592678-Fungi,
pubmed-meshheading:1592678-Insecticides,
pubmed-meshheading:1592678-Magnetic Resonance Spectroscopy,
pubmed-meshheading:1592678-Microbial Sensitivity Tests,
pubmed-meshheading:1592678-Microbiological Techniques,
pubmed-meshheading:1592678-Mites,
pubmed-meshheading:1592678-Molecular Weight,
pubmed-meshheading:1592678-Spectrophotometry, Infrared,
pubmed-meshheading:1592678-Stereoisomerism,
pubmed-meshheading:1592678-Streptomyces
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pubmed:year |
1992
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pubmed:articleTitle |
AB3217-A, a novel anti-mite substance produced by a strain of Streptomyces platensis.
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pubmed:affiliation |
Central Research Laboratories, Hokko Chemical Industry Co., Ltd., Kanagawa, Japan.
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pubmed:publicationType |
Journal Article
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