Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2005-5-31
pubmed:abstractText
Intravital microscopy (IVM) enables the study of cellular and molecular events in living organisms. Confocal microscopy permits images to be collected from narrow focal planes without interference from out-of-focus regions, and multi-photon microscopy produces high-resolution images from deep (several hundred micrometers) within opaque organs and tissues. Lasers that are targeted through microscope objectives can injure individual microvessels and induce thrombi that can be studied in detail. The marriage of these technologies provides exciting possibilities for investigating the inflammation and coagulation that is associated with disseminated intravascular coagulation (DIC). In this review, I consider some of the new technology associated with microscopy, give examples of discoveries that have been made using this technology and speculate on how the study of DIC might be advanced using IVM.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0165-6147
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
327-32
pubmed:dateRevised
2007-8-13
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Techniques: Intravital microscopy--a method for investigating disseminated intravascular coagulation?
pubmed:affiliation
Cardiovascular Research Unit, University of Sheffield, Clinical Sciences Centre, Northern General Hospital, Sheffield S5 7AU, UK. k.norman@sheffield.ac.uk
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't