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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
13
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pubmed:dateCreated |
2005-7-4
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pubmed:abstractText |
RNA chaperones are ubiquitous proteins that play pivotal roles in cellular RNA metabolism and RNA virus replication. Here we propose that they act by organizing complex and highly dynamic networks of RNA-RNA, RNA-protein and protein-protein interactions. How this is achieved and how their malfunction may lead to disease will be discussed through the examples of human immunodeficiency virus type 1 nucleocapsid protein (NCp7), the fragile X mental retardation protein and the prion protein.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Capsid Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/FMR1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Fragile X Mental Retardation Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Gene Products, gag,
http://linkedlifedata.com/resource/pubmed/chemical/Molecular Chaperones,
http://linkedlifedata.com/resource/pubmed/chemical/NCP7 protein, Human...,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Prions,
http://linkedlifedata.com/resource/pubmed/chemical/RNA,
http://linkedlifedata.com/resource/pubmed/chemical/RNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Viral Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/gag Gene Products, Human...
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1420-682X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1409-17
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15924259-Animals,
pubmed-meshheading:15924259-Capsid Proteins,
pubmed-meshheading:15924259-Fragile X Mental Retardation Protein,
pubmed-meshheading:15924259-Fragile X Syndrome,
pubmed-meshheading:15924259-Gene Products, gag,
pubmed-meshheading:15924259-HIV Infections,
pubmed-meshheading:15924259-HIV-1,
pubmed-meshheading:15924259-Humans,
pubmed-meshheading:15924259-Intellectual Disability,
pubmed-meshheading:15924259-Molecular Chaperones,
pubmed-meshheading:15924259-Nerve Tissue Proteins,
pubmed-meshheading:15924259-Prion Diseases,
pubmed-meshheading:15924259-Prions,
pubmed-meshheading:15924259-Protein Conformation,
pubmed-meshheading:15924259-RNA,
pubmed-meshheading:15924259-RNA-Binding Proteins,
pubmed-meshheading:15924259-Structure-Activity Relationship,
pubmed-meshheading:15924259-Viral Proteins,
pubmed-meshheading:15924259-gag Gene Products, Human Immunodeficiency Virus
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pubmed:year |
2005
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pubmed:articleTitle |
Disordered RNA chaperone proteins: from functions to disease.
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pubmed:affiliation |
Unité de Virologie Humaine (412), Ecole Normale Supérieure de Lyon et Institut National de la Santé et de la Recherche Médicale, IFR 128, 46 allée d'Italie, 69 364 Lyon, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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