rdf:type |
|
lifeskim:mentions |
umls-concept:C0008976,
umls-concept:C0012634,
umls-concept:C0015127,
umls-concept:C0024117,
umls-concept:C0030705,
umls-concept:C0073992,
umls-concept:C0082607,
umls-concept:C0087111,
umls-concept:C0117996,
umls-concept:C0205195,
umls-concept:C0205253,
umls-concept:C0868945,
umls-concept:C1314792,
umls-concept:C2587213,
umls-concept:C2825032
|
pubmed:issue |
6
|
pubmed:dateCreated |
2005-5-30
|
pubmed:abstractText |
Guidelines recommend inhaled corticosteroids (ICS) as maintenance treatment for patients with chronic obstructive pulmonary disease (COPD) with a post-bronchodilator forced expiratory volume in 1 second (FEV1) <50% predicted and frequent exacerbations, although they have only a small preventive effect on the accelerated decline in lung function. Combined treatment with ICS and long acting beta2 agonists (LABA) may provide benefit to the stability of COPD, but it is unknown if withdrawal of ICS will result in disease deterioration.
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-10208192,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-10359405,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-10379018,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-10464871,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-10806163,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-10807619,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-11500334,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-11641515,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-11734451,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-11936514,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-12030736,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-12379552,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-12406823,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-12570111,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-12570112,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-12583942,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-12647938,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-12970006,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-14586043,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-14680078,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-14680081,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-14985544,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-15215485,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-15668734,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-9105068,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-9150318,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-9150319,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15923248-9519948
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0040-6376
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
60
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
480-7
|
pubmed:dateRevised |
2009-11-18
|
pubmed:meshHeading |
pubmed-meshheading:15923248-Administration, Inhalation,
pubmed-meshheading:15923248-Albuterol,
pubmed-meshheading:15923248-Analysis of Variance,
pubmed-meshheading:15923248-Androstadienes,
pubmed-meshheading:15923248-Bronchodilator Agents,
pubmed-meshheading:15923248-Double-Blind Method,
pubmed-meshheading:15923248-Drug Combinations,
pubmed-meshheading:15923248-Female,
pubmed-meshheading:15923248-Humans,
pubmed-meshheading:15923248-Male,
pubmed-meshheading:15923248-Medical Records,
pubmed-meshheading:15923248-Middle Aged,
pubmed-meshheading:15923248-Pulmonary Disease, Chronic Obstructive,
pubmed-meshheading:15923248-Respiratory Function Tests,
pubmed-meshheading:15923248-Substance Withdrawal Syndrome
|
pubmed:year |
2005
|
pubmed:articleTitle |
Withdrawal of fluticasone propionate from combined salmeterol/fluticasone treatment in patients with COPD causes immediate and sustained disease deterioration: a randomised controlled trial.
|
pubmed:affiliation |
Department of Respiratory Medicine, University Hospital Maastricht, The Netherlands.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|