|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0016278,
umls-concept:C0033684,
umls-concept:C0056997,
umls-concept:C0086418,
umls-concept:C0205263,
umls-concept:C0521009,
umls-concept:C0677626,
umls-concept:C1160185,
umls-concept:C1514562,
umls-concept:C1708111,
umls-concept:C2265629,
umls-concept:C2347610
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|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2005-8-8
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|
pubmed:abstractText |
This study investigates the application of protein based therapeutic suicide enzyme/prodrug approaches providing novel means for both safe and effective local therapeutic regimes in solid tumors.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
|
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pubmed:issn |
0168-8278
|
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
43
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
442-50
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pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:15922474-Animals,
pubmed-meshheading:15922474-Base Sequence,
pubmed-meshheading:15922474-Carcinoma, Hepatocellular,
pubmed-meshheading:15922474-Cell Line, Tumor,
pubmed-meshheading:15922474-Cell Membrane Permeability,
pubmed-meshheading:15922474-Cytosine Deaminase,
pubmed-meshheading:15922474-DNA Primers,
pubmed-meshheading:15922474-Escherichia coli,
pubmed-meshheading:15922474-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:15922474-Fluorouracil,
pubmed-meshheading:15922474-Gene Amplification,
pubmed-meshheading:15922474-Hepatitis B virus,
pubmed-meshheading:15922474-Humans,
pubmed-meshheading:15922474-Liver Neoplasms,
pubmed-meshheading:15922474-Models, Molecular,
pubmed-meshheading:15922474-Protein Conformation,
pubmed-meshheading:15922474-Protein Transport,
pubmed-meshheading:15922474-Rabbits,
pubmed-meshheading:15922474-Recombinant Fusion Proteins
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|
pubmed:year |
2005
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|
pubmed:articleTitle |
Protein transduction with bacterial cytosine deaminase fused to the TLM intercellular transport motif induces profound chemosensitivity to 5-fluorocytosine in human hepatoma cells.
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pubmed:affiliation |
Robert Koch-Institute, Nordufer 20, D-13353 Berlin, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
