Source:http://linkedlifedata.com/resource/pubmed/id/15921421
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
2005-5-30
|
| pubmed:abstractText |
Phytochemical investigation of Eupatorium kiirunense has resulted in the isolation of eight new sesquiterpene lactones, constituted by five germacranolides, eupakirunsins A-E (1-5), and three heliangolides, eupaheliangolide A (6), 15-acetoxyheliangin (7), and 3-epi-heliangin (8), in addition to the known heliangin (9) and 8,10-epoxy-9-acetoxythymol angelate (10). The structures of the new compounds were established through detailed analysis of their spectroscopic data. Compounds 6, 8, and 9 exhibited cytotoxicity against human oral epidermoid (KB), cervical epitheloid (Hela), and liver (hepa59T/VGH) carcinoma cells.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0163-3864
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
68
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
745-50
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| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:15921421-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:15921421-Drug Screening Assays, Antitumor,
pubmed-meshheading:15921421-Eupatorium,
pubmed-meshheading:15921421-HeLa Cells,
pubmed-meshheading:15921421-Humans,
pubmed-meshheading:15921421-KB Cells,
pubmed-meshheading:15921421-Lactones,
pubmed-meshheading:15921421-Molecular Structure,
pubmed-meshheading:15921421-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:15921421-Plant Leaves,
pubmed-meshheading:15921421-Plants, Medicinal,
pubmed-meshheading:15921421-Sesquiterpenes,
pubmed-meshheading:15921421-Taiwan,
pubmed-meshheading:15921421-Tumor Cells, Cultured
|
| pubmed:year |
2005
|
| pubmed:articleTitle |
Cytotoxic sesquiterpene lactones from Eupatorium kiirunense, a coastal plant of Taiwan.
|
| pubmed:affiliation |
Institute of Marine Resources, National Sun Yat-sen University, 70 Lien-Hai Road, Kaohsiung, Taiwan 80424, Republic of China.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|