Source:http://linkedlifedata.com/resource/pubmed/id/15919620
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2005-5-27
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pubmed:abstractText |
Typhoid fever, caused by Salmonella enterica seroptype Typhi (S typhi), has an estimated worldwide prevalence of 12-33 million cases. The pathogenesis of this disease depends on the ingested inoculum size of S typhi, the virulence of the strain, the host's immune response and previous exposure, and local protective factors. Numerous extra-intestinal complications can occur with S typhi infection, including the involvement of the central nervous system (3-35%), cardiovascular system (1-5%), pulmonary system (1-86%), bone and joints (< or =1%), hepatobiliary system (1-26%), genitourinary system (<1%), and others. Due to an increase in multidrug-resistant S typhi, fluoroquinolones and third-generation cephalosporins have been increasingly used for typhoid fever and its complications. We describe the epidemiology, clinical manifestations, pathogenesis, and treatment of extra-intestinal S typhi infections.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1473-3099
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
341-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15919620-Anti-Bacterial Agents,
pubmed-meshheading:15919620-Bone Diseases,
pubmed-meshheading:15919620-Cardiovascular Diseases,
pubmed-meshheading:15919620-Central Nervous System Bacterial Infections,
pubmed-meshheading:15919620-Drug Resistance, Multiple, Bacterial,
pubmed-meshheading:15919620-Female Urogenital Diseases,
pubmed-meshheading:15919620-Humans,
pubmed-meshheading:15919620-Joint Diseases,
pubmed-meshheading:15919620-Male Urogenital Diseases,
pubmed-meshheading:15919620-Respiratory Tract Diseases,
pubmed-meshheading:15919620-Salmonella typhi,
pubmed-meshheading:15919620-Typhoid Fever
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pubmed:year |
2005
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pubmed:articleTitle |
Problem pathogens: extra-intestinal complications of Salmonella enterica serotype Typhi infection.
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pubmed:affiliation |
Center for Infectious Diseases, Baylor College of Medicine, Houston, Texas 77030, USA. dhuang1@bcm.tmc.edu
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pubmed:publicationType |
Journal Article,
Review
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