|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2005-5-25
|
|
pubmed:abstractText |
Mutations in the human Crumbs homologue 1 (CRB1) gene are a frequent cause of Leber congenital amaurosis (LCA) and various forms of retinitis pigmentosa. CRB1 is thought to organize an intracellular protein scaffold in the retina that is involved in photoreceptor polarity. This study was focused on the identification, subcellular localization, and binding characteristics of a novel member of the protein scaffold connected to CRB1.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CRB1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Eye Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/MPP4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/MPP5 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Mpp4 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Mpp5 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nucleoside-Phosphate Kinase,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0146-0404
|
|
pubmed:author |
pubmed-author:AlexeevaSvetlanaS,
pubmed-author:CremersFrans P MFP,
pubmed-author:GosensIlseI,
pubmed-author:KantardzhievaAlbenaA,
pubmed-author:KloosterJanJ,
pubmed-author:KriegerElmarE,
pubmed-author:LetteboerStef J FSJ,
pubmed-author:Neefjes-MolCarla ACA,
pubmed-author:PunteIngrid MIM,
pubmed-author:RoepmanRonaldR,
pubmed-author:VersteegIngeI,
pubmed-author:WijnholdsJanJ,
pubmed-author:den HollanderAnneke IAI
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
46
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2192-201
|
|
pubmed:dateRevised |
2008-11-21
|
|
pubmed:meshHeading |
pubmed-meshheading:15914641-Animals,
pubmed-meshheading:15914641-Blotting, Western,
pubmed-meshheading:15914641-Cell Polarity,
pubmed-meshheading:15914641-Dogs,
pubmed-meshheading:15914641-Eye Proteins,
pubmed-meshheading:15914641-Humans,
pubmed-meshheading:15914641-Immunohistochemistry,
pubmed-meshheading:15914641-Membrane Proteins,
pubmed-meshheading:15914641-Microscopy, Confocal,
pubmed-meshheading:15914641-Microscopy, Immunoelectron,
pubmed-meshheading:15914641-Models, Molecular,
pubmed-meshheading:15914641-Nerve Tissue Proteins,
pubmed-meshheading:15914641-Nucleoside-Phosphate Kinase,
pubmed-meshheading:15914641-Photoreceptor Cells, Vertebrate,
pubmed-meshheading:15914641-Protein Binding,
pubmed-meshheading:15914641-RNA, Messenger,
pubmed-meshheading:15914641-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:15914641-Two-Hybrid System Techniques
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
MPP5 recruits MPP4 to the CRB1 complex in photoreceptors.
|
|
pubmed:affiliation |
Netherlands Ophthalmic Research Institute, Amsterdam.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
