Linked Life Data

1591352

Source:http://linkedlifedata.com/resource/pubmed/id/1591352

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1992-6-26
pubmed:abstractText
Characteristics of preimplantation embryonic development to Day 3.5 of gestation were evaluated in lines of mice after 21 generations of selection for litter size or components of litter size. Selection criteria were direct selection for number born (LS), selection on an index of ovulation rate and the proportion of ova shed that resulted in fully formed pups (IX), selection for number born in unilaterally ovariectomized females as an indication of uterine capacity (UT), and an unselected control (LC). Comparison of the average distributions of embryonic stage of development on the left side of the uterus showed that selection (average effect of LS, IX, and UT vs. LC) tended to advance (p = 0.07) the average stage of embryonic development at Day 3.5 and shift the distribution (p = 0.10) by increasing the frequency of expanded blastocysts and decreasing the frequency of pre-morula embryos. A similar shift in the distribution on the right side of the uterus was not statistically significant. Selection decreased (p = 0.06) variability in developmental stage among embryos within the right uterine horn. These selection criteria evaluated in the mouse appear to have changed the frequencies of genes that affect some determinants of average stage of embryonic development and uniformity of development within a uterine horn at Day 3.5 of gestation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0006-3363
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
958-63
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Effects of three methods of selection for litter size in mice on pre-implantation embryonic development.
pubmed:affiliation
Oklahoma Agricultural Experiment Station, Stillwater 74078.
pubmed:publicationType
Journal Article, Comparative Study