Linked Life Data

1591294

Source:http://linkedlifedata.com/resource/pubmed/id/1591294

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1992-7-1
pubmed:abstractText
The goal of therapy for young adults with de novo acute myeloid leukemia is cure. Seventy percent or more of young adults achieve initial remission, and 30% to 40% of adults receiving postremission chemotherapy appear to remain in remission. High-dose cytarabine consolidation therapy appears particularly effective. However, with current approaches, only 20% of young adults are cured. New approaches are needed to increase the cure rate substantially, and autologous bone marrow transplantation appears to be the most promising treatment modality in acute myeloid leukemia. Improved preparative regimens and purging techniques may be critical factors in determining the effectiveness of autologous bone marrow transplantation. In adult acute lymphoblastic leukemia, very high remission rates are now being reported with intensive multiagent induction therapy, and approximately one third of young adults with this disease are cured with current intensive chemotherapy approaches. The role and optimal methods of bone marrow transplantation for acute lymphoblastic leukemia are under investigation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1040-8746
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
53-65
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Treatment of acute leukemia in adults.
pubmed:affiliation
University of California, San Francisco.
pubmed:publicationType
Journal Article, Review