Source:http://linkedlifedata.com/resource/pubmed/id/15912297
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2005-5-24
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pubmed:abstractText |
We report a rare case of a solitary metachronous metastasis of renal clear cell carcinoma (RCC) presenting as a thyroid tumor 19 years after a nephrectomy. Our search of the English-language literature found only sporadic reports of late RCC metastases to the thyroid. Fine-needle aspiration biopsy of the thyroid tumor was not accompanied with thyroglobulin (Tg) staining, leading us to initially suspect a primary follicular thyroid carcinoma. The patient, a 77-year-old man, underwent a total thyroidectomy with modified neck dissection. Histological examination confirmed the tumor to be RCC metastasis, and immunohistochemical analysis revealed that both Tg and thyroid transcription factor-1 (TTF-1) were negative in the tumor cells. Thus, the possibility of late RCC metastasis to the thyroid should be considered, even in a patient with a remote history. Furthermore, TTF-1 is useful for identifying thyroid metastatic carcinomas.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0941-1291
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
483-7
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pubmed:dateRevised |
2006-8-3
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pubmed:meshHeading |
pubmed-meshheading:15912297-Aged,
pubmed-meshheading:15912297-Carcinoma, Renal Cell,
pubmed-meshheading:15912297-Humans,
pubmed-meshheading:15912297-Immunohistochemistry,
pubmed-meshheading:15912297-Kidney Neoplasms,
pubmed-meshheading:15912297-Lymph Node Excision,
pubmed-meshheading:15912297-Male,
pubmed-meshheading:15912297-Nuclear Proteins,
pubmed-meshheading:15912297-Thyroglobulin,
pubmed-meshheading:15912297-Thyroid Neoplasms,
pubmed-meshheading:15912297-Thyroidectomy,
pubmed-meshheading:15912297-Time Factors,
pubmed-meshheading:15912297-Transcription Factors
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pubmed:year |
2005
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pubmed:articleTitle |
Solitary metachronous metastasis to the thyroid from renal clear cell carcinoma 19 years after nephrectomy: report of a case.
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pubmed:affiliation |
Department of General Surgery, Yokohama City University Medical Center, 4-57 Urafune-cho, Yokohama, 232-0024, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
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