Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2005-5-24
pubmed:abstractText
A user-friendly, advanced software package for gene design is described. The software comprises an integrated suite of programs-also provided as stand-alone tools-that automatically performs the following tasks in gene design: restriction site prediction, codon optimization for any expression host, restriction site inclusion and exclusion, separation of long sequences into synthesizable fragments, T(m) and stem-loop determinations, optimal oligonucleotide component design and design verification/error-checking. The output is a complete design report and a list of optimized oligonucleotides to be prepared for subsequent gene synthesis. The user interface accommodates both inexperienced and experienced users. For inexperienced users, explanatory notes are provided such that detailed instructions are not necessary; for experienced users, a streamlined interface is provided without such notes. The software has been extensively tested in the design and successful synthesis of over 400 kb of genes, many of which exceeded 5 kb in length.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/15911632-10611405, http://linkedlifedata.com/resource/pubmed/commentcorrection/15911632-10827456, http://linkedlifedata.com/resource/pubmed/commentcorrection/15911632-12000848, http://linkedlifedata.com/resource/pubmed/commentcorrection/15911632-14602936, http://linkedlifedata.com/resource/pubmed/commentcorrection/15911632-15215375, http://linkedlifedata.com/resource/pubmed/commentcorrection/15911632-15240836, http://linkedlifedata.com/resource/pubmed/commentcorrection/15911632-15283197, http://linkedlifedata.com/resource/pubmed/commentcorrection/15911632-15496466, http://linkedlifedata.com/resource/pubmed/commentcorrection/15911632-2223068, http://linkedlifedata.com/resource/pubmed/commentcorrection/15911632-2725322, http://linkedlifedata.com/resource/pubmed/commentcorrection/15911632-3265397, http://linkedlifedata.com/resource/pubmed/commentcorrection/15911632-3459152, http://linkedlifedata.com/resource/pubmed/commentcorrection/15911632-7590320
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1362-4962
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3011-6
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
GeMS: an advanced software package for designing synthetic genes.
pubmed:affiliation
KOSAN Biosciences Inc. 3832 Bay Center Place, Hayward, CA 94545, USA.
pubmed:publicationType
Journal Article