| pubmed-article:15911271 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15911271 | lifeskim:mentions | umls-concept:C0021467 | lld:lifeskim |
| pubmed-article:15911271 | lifeskim:mentions | umls-concept:C1150571 | lld:lifeskim |
| pubmed-article:15911271 | lifeskim:mentions | umls-concept:C0021469 | lld:lifeskim |
| pubmed-article:15911271 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:15911271 | pubmed:dateCreated | 2005-5-24 | lld:pubmed |
| pubmed-article:15911271 | pubmed:abstractText | A series of 21 novel 2-[(aminocarbonyl)amino]-5-acetylenyl-3-thiophenecarboxamides were synthesized and evaluated for the inhibition of IKK-2. In spite of their often modest activity on the enzyme, six selected analogs showed significant inhibition of the production of inflammatory cytokine IL-8 in IL-1beta stimulated rheumatoid arthritis-derived synovial fibroblasts, demonstrating their potential usefulness as NF-kappaB regulators. | lld:pubmed |
| pubmed-article:15911271 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15911271 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15911271 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15911271 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15911271 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15911271 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15911271 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15911271 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15911271 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15911271 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15911271 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15911271 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:15911271 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:15911271 | pubmed:author | pubmed-author:KenY HYH | lld:pubmed |
| pubmed-article:15911271 | pubmed:author | pubmed-author:KishoreNandin... | lld:pubmed |
| pubmed-article:15911271 | pubmed:author | pubmed-author:MathialaganSu... | lld:pubmed |
| pubmed-article:15911271 | pubmed:author | pubmed-author:RouwSharonS | lld:pubmed |
| pubmed-article:15911271 | pubmed:author | pubmed-author:DonnellyAnnA | lld:pubmed |
| pubmed-article:15911271 | pubmed:author | pubmed-author:ClareMichaelM | lld:pubmed |
| pubmed-article:15911271 | pubmed:author | pubmed-author:SommersCindyC | lld:pubmed |
| pubmed-article:15911271 | pubmed:author | pubmed-author:GuzovaJuliaJ | lld:pubmed |
| pubmed-article:15911271 | pubmed:author | pubmed-author:BonarSheriS | lld:pubmed |
| pubmed-article:15911271 | pubmed:author | pubmed-author:WeierRichardR | lld:pubmed |
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| pubmed-article:15911271 | pubmed:author | pubmed-author:TrippCatherin... | lld:pubmed |
| pubmed-article:15911271 | pubmed:author | pubmed-author:WolfsonSergeS | lld:pubmed |
| pubmed-article:15911271 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15911271 | pubmed:day | 2 | lld:pubmed |
| pubmed-article:15911271 | pubmed:volume | 15 | lld:pubmed |
| pubmed-article:15911271 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15911271 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15911271 | pubmed:pagination | 2870-5 | lld:pubmed |
| pubmed-article:15911271 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:15911271 | pubmed:meshHeading | pubmed-meshheading:15911271... | lld:pubmed |
| pubmed-article:15911271 | pubmed:meshHeading | pubmed-meshheading:15911271... | lld:pubmed |
| pubmed-article:15911271 | pubmed:meshHeading | pubmed-meshheading:15911271... | lld:pubmed |
| pubmed-article:15911271 | pubmed:meshHeading | pubmed-meshheading:15911271... | lld:pubmed |
| pubmed-article:15911271 | pubmed:meshHeading | pubmed-meshheading:15911271... | lld:pubmed |
| pubmed-article:15911271 | pubmed:meshHeading | pubmed-meshheading:15911271... | lld:pubmed |
| pubmed-article:15911271 | pubmed:meshHeading | pubmed-meshheading:15911271... | lld:pubmed |
| pubmed-article:15911271 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15911271 | pubmed:articleTitle | Inhibition of IKK-2 by 2-[(aminocarbonyl)amino]-5-acetylenyl-3-thiophenecarboxamides. | lld:pubmed |
| pubmed-article:15911271 | pubmed:affiliation | Department of Medicinal Chemistry, Pfizer Inc., St Louis, MO 63017, USA. bonafoux@biogenidec.com | lld:pubmed |
| pubmed-article:15911271 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:15911271 | lld:chembl |
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