rdf:type |
|
lifeskim:mentions |
umls-concept:C0013485,
umls-concept:C0035696,
umls-concept:C0040845,
umls-concept:C0050668,
umls-concept:C0150312,
umls-concept:C0162508,
umls-concept:C0205217,
umls-concept:C0525037,
umls-concept:C1413292,
umls-concept:C1423526,
umls-concept:C2753500
|
pubmed:issue |
3
|
pubmed:dateCreated |
1992-6-23
|
pubmed:abstractText |
Activin and retinoids, which are involved in the induction and regulation of the early differentiation process in vertebrate embryogenesis, synergistically increased the amount of c-jun mRNA in P19 embryonal carcinoma cells, but activin alone had no effect. Among the retinoids, all-trans-retinoic acid most effectively increased c-jun mRNA. Activin (lng/ml) was sufficient to induce the synergistic increase of c-jun mRNA in P19 EC cells with all-trans-retinoic acid. The synergistic increase of the amount of c-jun mRNA by their cooperative action may be important in vertebrate development.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0006-291X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
184
|
pubmed:geneSymbol |
c-jun
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1350-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:1590797-Activins,
pubmed-meshheading:1590797-Animals,
pubmed-meshheading:1590797-Cell Line,
pubmed-meshheading:1590797-Drug Synergism,
pubmed-meshheading:1590797-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:1590797-Genes, jun,
pubmed-meshheading:1590797-Growth Substances,
pubmed-meshheading:1590797-Inhibins,
pubmed-meshheading:1590797-Kinetics,
pubmed-meshheading:1590797-Mice,
pubmed-meshheading:1590797-RNA, Messenger,
pubmed-meshheading:1590797-Teratoma,
pubmed-meshheading:1590797-Transcription, Genetic,
pubmed-meshheading:1590797-Tretinoin
|
pubmed:year |
1992
|
pubmed:articleTitle |
Activin synergistically increased c-jun mRNA in P19 embryonal carcinoma cells in the presence of retinoic acid.
|
pubmed:affiliation |
National Institute of Neuroscience, NCNP, Tokyo, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|