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rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0024204,
umls-concept:C0027651,
umls-concept:C0036525,
umls-concept:C0185117,
umls-concept:C0623362,
umls-concept:C0936012,
umls-concept:C0940978,
umls-concept:C1514307,
umls-concept:C1522484,
umls-concept:C2911684
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|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2005-5-25
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|
pubmed:abstractText |
Matrix metalloproteinases (MMP) are endogenous peptidases capable of degrading various components of the basement membrane. The ability of malignant epithelial cells to degrade extracellular matrix and basement membrane is an important step in the process of metastatic invasion. In this study, we prospectively compared the outcome of patients undergoing laparotomy for resection of periampullary malignancies with lymph node and tumor MMP expression to determine if there was a correlation between metalloproteinase expression and patient outcome.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0022-4790
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
15
|
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pubmed:volume |
90
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
239-46
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15906368-Adenocarcinoma,
pubmed-meshheading:15906368-Aged,
pubmed-meshheading:15906368-Ampulla of Vater,
pubmed-meshheading:15906368-Common Bile Duct Neoplasms,
pubmed-meshheading:15906368-Female,
pubmed-meshheading:15906368-Forecasting,
pubmed-meshheading:15906368-Humans,
pubmed-meshheading:15906368-Lymph Nodes,
pubmed-meshheading:15906368-Lymphatic Metastasis,
pubmed-meshheading:15906368-Male,
pubmed-meshheading:15906368-Matrix Metalloproteinase 2,
pubmed-meshheading:15906368-Matrix Metalloproteinase 9,
pubmed-meshheading:15906368-Matrix Metalloproteinases,
pubmed-meshheading:15906368-Middle Aged,
pubmed-meshheading:15906368-Prognosis,
pubmed-meshheading:15906368-RNA, Messenger,
pubmed-meshheading:15906368-Survival Rate,
pubmed-meshheading:15906368-Tissue Inhibitor of Metalloproteinase-2,
pubmed-meshheading:15906368-Tissue Inhibitor of Metalloproteinases
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|
pubmed:year |
2005
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|
pubmed:articleTitle |
Predictive value of lymph node and tumor matrix metalloproteinase expression in the analysis of metastatic periampullary tumors.
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pubmed:affiliation |
Department of Surgery, Vancouver Hospital and Health Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.
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pubmed:publicationType |
Journal Article
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