Source:http://linkedlifedata.com/resource/pubmed/id/15902723
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
19
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pubmed:dateCreated |
2005-5-19
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pubmed:abstractText |
To translate Tet-on system into a conditional mouse model, in which hepatitis B or C virus (HBV or HCV) gene could be spatiotemporally expressed to overcome "immune tolerance" formed during the embryonic development and "immune escape" against hepatitis virus antigen(s), an effector mouse, carrying the reverse tetracycline-responsive transcriptional activator (rtTA) gene under the tight control of liver-specific human apoE promoter, is required to be generated.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1007-9327
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2885-91
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15902723-Animals,
pubmed-meshheading:15902723-Apolipoproteins E,
pubmed-meshheading:15902723-Hepatitis C,
pubmed-meshheading:15902723-Hepatitis C Antigens,
pubmed-meshheading:15902723-Immune Tolerance,
pubmed-meshheading:15902723-Liver,
pubmed-meshheading:15902723-Mice,
pubmed-meshheading:15902723-Mice, Transgenic,
pubmed-meshheading:15902723-Promoter Regions, Genetic,
pubmed-meshheading:15902723-Tetracycline,
pubmed-meshheading:15902723-Trans-Activators,
pubmed-meshheading:15902723-Transgenes
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pubmed:year |
2005
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pubmed:articleTitle |
Generation of the regulatory protein rtTA transgenic mice.
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pubmed:affiliation |
Center of Experimental Animals, Sun Yat-Sen (Zhongshan) University, No. 74, Zhongshan Road 2, Guangzhou 510080, Guangdong Province, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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