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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1992-6-25
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pubmed:abstractText |
Nine patients with complicated hydatid disease managed with surgery and mebendazole/albendazole are presented. Five patients received albendazole (1 treatment course) and 5 patients received mebendazole (3 had 2 treatment courses, 1 had a switch-over from mebendazole to albendazole). The mean durations of treatment and follow-up were respectively 7 +/- 2.5 months and 7 +/- 2.5 months (albendazole); 13 +/- 10 months and 29 +/- 31 months (mebendazole). A superior clinical and radiological response was seen in 1 patient with disseminated intra-abdominal disease on switching therapy from mebendazole to albendazole. Radiological improvement occurred in 3/5 courses of albendazole and in 2/8 courses of mebendazole. Clinical improvement occurred in 3/5 courses of albendazole and 0/8 courses of mebendazole. Radiological deterioration was demonstrated in 0/5 courses of albendazole and 2/8 courses of mebendazole. Although the impression was that albendazole was superior, good responses were also seen with mebendazole. The heterogeneity of the patients, their disease, short follow-up time, lack of more sensitive noninvasive assay techniques urges caution before firm conclusions can be drawn.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0036-5548
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-13
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1589713-Abdomen,
pubmed-meshheading:1589713-Adult,
pubmed-meshheading:1589713-Aged,
pubmed-meshheading:1589713-Albendazole,
pubmed-meshheading:1589713-Child,
pubmed-meshheading:1589713-Debridement,
pubmed-meshheading:1589713-Drug Therapy, Combination,
pubmed-meshheading:1589713-Echinococcosis,
pubmed-meshheading:1589713-Echinococcosis, Hepatic,
pubmed-meshheading:1589713-Female,
pubmed-meshheading:1589713-Humans,
pubmed-meshheading:1589713-Male,
pubmed-meshheading:1589713-Mebendazole,
pubmed-meshheading:1589713-Middle Aged,
pubmed-meshheading:1589713-Time Factors,
pubmed-meshheading:1589713-Tomography, X-Ray Computed
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pubmed:year |
1992
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pubmed:articleTitle |
A clinical-radiological evaluation of benzimidazoles in the management of Echinococcus granulosus cysts.
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pubmed:affiliation |
Department of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
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pubmed:publicationType |
Journal Article,
Case Reports
|