Linked Life Data

15894685

Source:http://linkedlifedata.com/resource/pubmed/id/15894685

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2005-5-16
pubmed:abstractText
Zinc is involved in several physiologic processes, including cell growth and proliferation. Although in normal prostate tissue zinc levels are high, there is a marked decrease in prostate cancer. Metallothioneins control the bioavailability of zinc and one isoform, MT1G, was reported down-regulated in prostate cancer. Here, we investigated whether promoter methylation might cause MT1G silencing in prostate cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1055-9965
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1274-8
pubmed:dateRevised
2010-3-23
pubmed:meshHeading
pubmed-meshheading:15894685-Adenocarcinoma, pubmed-meshheading:15894685-Aged, pubmed-meshheading:15894685-Analysis of Variance, pubmed-meshheading:15894685-Cell Line, Tumor, pubmed-meshheading:15894685-Cell Proliferation, pubmed-meshheading:15894685-DNA Methylation, pubmed-meshheading:15894685-Disease Progression, pubmed-meshheading:15894685-Gene Expression Regulation, Neoplastic, pubmed-meshheading:15894685-Gene Silencing, pubmed-meshheading:15894685-Humans, pubmed-meshheading:15894685-Male, pubmed-meshheading:15894685-Metallothionein, pubmed-meshheading:15894685-Middle Aged, pubmed-meshheading:15894685-Neoplasm Staging, pubmed-meshheading:15894685-Polymerase Chain Reaction, pubmed-meshheading:15894685-Promoter Regions, Genetic, pubmed-meshheading:15894685-Prostatic Intraepithelial Neoplasia, pubmed-meshheading:15894685-Prostatic Neoplasms, pubmed-meshheading:15894685-RNA, pubmed-meshheading:15894685-Tumor Markers, Biological, pubmed-meshheading:15894685-Zinc
pubmed:year
2005
pubmed:articleTitle
MT1G hypermethylation is associated with higher tumor stage in prostate cancer.
pubmed:affiliation
Department of Genetics, Portuguese Oncology Institute, Porto, Rua Dr. Antonio Bernardino Almeida, 4200-072 Porto, Portugal.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't