rdf:type |
|
lifeskim:mentions |
umls-concept:C0007113,
umls-concept:C0016360,
umls-concept:C0069717,
umls-concept:C0205179,
umls-concept:C0205390,
umls-concept:C0332174,
umls-concept:C0444889,
umls-concept:C0445204,
umls-concept:C1517927,
umls-concept:C1522449,
umls-concept:C2603343
|
pubmed:issue |
7
|
pubmed:dateCreated |
2005-6-20
|
pubmed:abstractText |
Oxaliplatin (OXA) significantly enhanced the antitumour activity of 5-fluorouracil (FUra) in patients with advanced colorectal cancer and displayed radiosensitising properties in preclinical studies. This study was thus performed to test the feasibility, identify the recommended doses (RDs) and explore preliminarily the clinical activity of weekly OXA and infused FUra combined with preoperative pelvic radiotherapy.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0923-7534
|
pubmed:author |
pubmed-author:AscheleCC,
pubmed-author:Del BiancoPP,
pubmed-author:FabrisGG,
pubmed-author:FrisoM LML,
pubmed-author:LiseMM,
pubmed-author:LonardiSS,
pubmed-author:MonfardiniSS,
pubmed-author:PucciarelliSS,
pubmed-author:SartorLL,
pubmed-author:SottiGG,
pubmed-author:UrsoE D LED
|
pubmed:issnType |
Print
|
pubmed:volume |
16
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1140-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15894548-Adult,
pubmed-meshheading:15894548-Aged,
pubmed-meshheading:15894548-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:15894548-Cohort Studies,
pubmed-meshheading:15894548-Drug Administration Schedule,
pubmed-meshheading:15894548-Female,
pubmed-meshheading:15894548-Fluorouracil,
pubmed-meshheading:15894548-Humans,
pubmed-meshheading:15894548-Infusions, Intravenous,
pubmed-meshheading:15894548-Male,
pubmed-meshheading:15894548-Middle Aged,
pubmed-meshheading:15894548-Organoplatinum Compounds,
pubmed-meshheading:15894548-Preoperative Care,
pubmed-meshheading:15894548-Rectal Neoplasms
|
pubmed:year |
2005
|
pubmed:articleTitle |
A phase I-II study of weekly oxaliplatin, 5-fluorouracil continuous infusion and preoperative radiotherapy in locally advanced rectal cancer.
|
pubmed:affiliation |
Department of Medical Oncology, Radiotherapy and Surgery, Padova University Hospital, Padova. aschele@tin.it
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase II,
Clinical Trial, Phase I
|