rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
25
|
pubmed:dateCreated |
1992-6-19
|
pubmed:abstractText |
Bronchial hyperresponsiveness to cholinergic stimuli such as the inhalation of methacholine is common in patients with impaired left ventricular function. Such hyperresponsiveness is best explained by cholinergic vasodilation of blood vessels in the small airways, with extravasation of plasma due to high left ventricular filling pressure. Because this vasodilation may be prevented by the inhalation of the vasoconstrictor agent methoxamine, we studied the effect of methoxamine on exercise performance in patients with chronic left ventricular dysfunction.
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pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0028-4793
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
18
|
pubmed:volume |
326
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1661-5
|
pubmed:dateRevised |
2010-3-24
|
pubmed:meshHeading |
pubmed-meshheading:1588979-Administration, Inhalation,
pubmed-meshheading:1588979-Cardiomyopathies,
pubmed-meshheading:1588979-Chronic Disease,
pubmed-meshheading:1588979-Coronary Disease,
pubmed-meshheading:1588979-Double-Blind Method,
pubmed-meshheading:1588979-Female,
pubmed-meshheading:1588979-Heart Failure,
pubmed-meshheading:1588979-Hemodynamics,
pubmed-meshheading:1588979-Humans,
pubmed-meshheading:1588979-Male,
pubmed-meshheading:1588979-Methoxamine,
pubmed-meshheading:1588979-Middle Aged,
pubmed-meshheading:1588979-Oxygen Consumption,
pubmed-meshheading:1588979-Physical Exertion,
pubmed-meshheading:1588979-Respiratory System,
pubmed-meshheading:1588979-Stroke Volume,
pubmed-meshheading:1588979-Vasodilation,
pubmed-meshheading:1588979-Ventricular Function, Left
|
pubmed:year |
1992
|
pubmed:articleTitle |
Improvement in exercise performance by inhalation of methoxamine in patients with impaired left ventricular function.
|
pubmed:affiliation |
Department of Cardiology, Hôpital Cochin, René Descartes University, Paris, France.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|