Source:http://linkedlifedata.com/resource/pubmed/id/15888937
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2005-5-12
|
pubmed:abstractText |
The need for new antifungal agents continues, fueled by opportunistic infections in immune-compromised patients and by the development of resistance to existing agents. Natural products offer a virtually unlimited source of unique molecules and not only serve as a reservoir for new potential drugs and drug prototypes, but also for probes of fungal biology. In this chapter, whole-cell screening methods targeted for natural products are illustrated, including general microplate-based screening, bioautography, and mode of action studies, including the use of genetically altered fungal strains now available commercially.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
1543-1894
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
118
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
83-109
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:15888937-Antifungal Agents,
pubmed-meshheading:15888937-Biological Agents,
pubmed-meshheading:15888937-Drug Evaluation, Preclinical,
pubmed-meshheading:15888937-Drug Resistance, Fungal,
pubmed-meshheading:15888937-Fungi,
pubmed-meshheading:15888937-Humans,
pubmed-meshheading:15888937-Microbial Sensitivity Tests,
pubmed-meshheading:15888937-Plant Extracts
|
pubmed:year |
2005
|
pubmed:articleTitle |
Natural products and antifungal drug discovery.
|
pubmed:affiliation |
National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, University, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
|