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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1992-6-25
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pubmed:abstractText |
Three novel methods, recently developed by us, for the synthesis of non-thrombogenetic materials were reviewed. The first was the utilization of poly(vinyl sulfonate) as a heparinoid and a newly synthesized polymerizable-thrombin-inhibitor. The chemicals were grafted onto the surfaces of materials. The second was the use of thrombin-substrate-analog peptide. The immobilized peptide was decomposed by blood coagulation factors and inhibited thrombus formation on the surface. The third method was the enhancement of endothelialization by immobilization of bio-signal molecules. The immobilized biosignals remarkably accelerated the growth of endothelial cells.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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|
pubmed:issn |
0885-3282
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
6
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|
pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
293-318
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1588484-Anticoagulants,
pubmed-meshheading:1588484-Antithrombin III,
pubmed-meshheading:1588484-Biocompatible Materials,
pubmed-meshheading:1588484-Fibrinogen,
pubmed-meshheading:1588484-Heparin,
pubmed-meshheading:1588484-Hydrolysis,
pubmed-meshheading:1588484-Models, Theoretical,
pubmed-meshheading:1588484-Polymers,
pubmed-meshheading:1588484-Surface Properties,
pubmed-meshheading:1588484-Thrombin,
pubmed-meshheading:1588484-Thrombosis
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|
pubmed:year |
1992
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|
pubmed:articleTitle |
Non-thrombogenicity by novel surface modification methods.
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pubmed:affiliation |
Department of Polymer Chemistry, Kyoto University, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
|
