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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2005-5-10
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pubmed:abstractText |
The authors describe 12 neuroleptic-treated patients with dementia of various etiologies who showed CSF elevation of phosphorylated 14-3-3zeta and normal tau protein levels. This contrasted with elevated amounts of 14-3-3 gamma, epsilon, and unphosphorylated zeta coupled to high tau protein levels in Creutzfeldt-Jakob disease and negative 14-3-3 assay in drug-free patients with dementia. Characterization of CSF 14-3-3 isoforms and determination of tau protein level can help to distinguish different etiologies of dementia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1526-632X
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pubmed:author |
pubmed-author:BenedettiM DMD,
pubmed-author:CapaldiSS,
pubmed-author:Dalla LiberaAA,
pubmed-author:FarinazzoAA,
pubmed-author:FerrariSS,
pubmed-author:FioriniMM,
pubmed-author:GelatiMM,
pubmed-author:MonacoH LHL,
pubmed-author:MonacoSS,
pubmed-author:RizzutoNN,
pubmed-author:ZanussoGG
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pubmed:issnType |
Electronic
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pubmed:day |
10
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1618-20
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15883327-14-3-3 Proteins,
pubmed-meshheading:15883327-Aged,
pubmed-meshheading:15883327-Aged, 80 and over,
pubmed-meshheading:15883327-Antipsychotic Agents,
pubmed-meshheading:15883327-Biological Markers,
pubmed-meshheading:15883327-Brain,
pubmed-meshheading:15883327-Creutzfeldt-Jakob Syndrome,
pubmed-meshheading:15883327-Dementia,
pubmed-meshheading:15883327-Diagnosis, Differential,
pubmed-meshheading:15883327-Female,
pubmed-meshheading:15883327-Humans,
pubmed-meshheading:15883327-Male,
pubmed-meshheading:15883327-Middle Aged,
pubmed-meshheading:15883327-Phosphorylation,
pubmed-meshheading:15883327-Predictive Value of Tests,
pubmed-meshheading:15883327-Protein Isoforms,
pubmed-meshheading:15883327-Reference Values,
pubmed-meshheading:15883327-Up-Regulation,
pubmed-meshheading:15883327-tau Proteins
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pubmed:year |
2005
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pubmed:articleTitle |
Phosphorylated 14-3-3zeta protein in the CSF of neuroleptic-treated patients.
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pubmed:affiliation |
Department of Neurological and Visual Sciences, University of Verona, Verona, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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