rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
2005-5-10
|
pubmed:abstractText |
The microtubule-associated tau protein abnormally phosphorylated at threonine 231 (p-tau231) has been investigated as a potential marker of Alzheimer disease. Levels of cerebrospinal fluid (CSF) p-tau231 vary across patients with Alzheimer disease. We hypothesized that these variations partially reflect differences in the degree of neuronal damage and therefore may be used to predict structural disease progression.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0003-9942
|
pubmed:author |
pubmed-author:BürgerKatharinaK,
pubmed-author:DaviesPeterP,
pubmed-author:DeBernardisJohnJ,
pubmed-author:EvansAlan CAC,
pubmed-author:HampelHaraldH,
pubmed-author:KerkmanDanielD,
pubmed-author:LeinsingerGerdaG,
pubmed-author:MöllerHans-JürgenHJ,
pubmed-author:PruessnerJens CJC,
pubmed-author:TeipelStefan JSJ,
pubmed-author:ZinkowskiRaymondR
|
pubmed:issnType |
Print
|
pubmed:volume |
62
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
770-3
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15883264-Aged,
pubmed-meshheading:15883264-Alzheimer Disease,
pubmed-meshheading:15883264-Atrophy,
pubmed-meshheading:15883264-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:15883264-Female,
pubmed-meshheading:15883264-Functional Laterality,
pubmed-meshheading:15883264-Hippocampus,
pubmed-meshheading:15883264-Humans,
pubmed-meshheading:15883264-Magnetic Resonance Imaging,
pubmed-meshheading:15883264-Male,
pubmed-meshheading:15883264-Mental Status Schedule,
pubmed-meshheading:15883264-Middle Aged,
pubmed-meshheading:15883264-Phosphorylation,
pubmed-meshheading:15883264-Statistics as Topic,
pubmed-meshheading:15883264-Threonine,
pubmed-meshheading:15883264-tau Proteins
|
pubmed:year |
2005
|
pubmed:articleTitle |
Correlation of cerebrospinal fluid levels of tau protein phosphorylated at threonine 231 with rates of hippocampal atrophy in Alzheimer disease.
|
pubmed:affiliation |
Alzheimer Memorial Center and Geriatric Psychiatry Branch, Dementia and Neuroimaging Section, Department of Psychiatry, Ludwig-Maximilian University, Munich, Germany.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|