Source:http://linkedlifedata.com/resource/pubmed/id/15882171
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2005-5-10
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pubmed:abstractText |
Efficiency of radiotherapy in controlling lymph node metastasis is a controversial issue. A continuous series of 87 patients affected by cervical cancer stages IB2-IVA and treated using pelvic radiotherapy is presented. A retrospective comparison is made between two populations. In the two populations, a staging lymphadenectomy was carried out before the onset of the therapeutic program. In the first population (53 patients), the pelvic nodes only were dissected and in the second one (34 patients), the pelvic lymph nodes were left in place and the paraaortic nodes only were dissected. In both series, a completion surgery was performed after finalization of the radiotherapy. It was carried out at open abdomen in both series. It included a systematic pelvic dissection for the patients whose pelvic nodes had been intentionally left in place at the time of the initial staging lymphadenectomy. Both series were identical as far as classic risk factors were concerned (FIGO stage, maximal tumor diameter, lymphovascular space involvement). The radiotherapy administered to the pelvis was the same in both populations. The number of patients with pelvic lymph node metastasis was 21 (39.6%) in the first population versus 6 (17.6%) in the second one (P = 0.03). The percentage of positive lymph nodes among the retrieved lymph nodes was 18.94 in the first population versus 2.8 in the second one (P = 0.0001). Pelvic radiotherapy is likely to control most of the pelvic lymph node metastasis, but not all of them. Practical deductions and further developments are discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1048-891X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
468-74
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15882171-Adult,
pubmed-meshheading:15882171-Female,
pubmed-meshheading:15882171-Humans,
pubmed-meshheading:15882171-Lymph Node Excision,
pubmed-meshheading:15882171-Lymphatic Metastasis,
pubmed-meshheading:15882171-Middle Aged,
pubmed-meshheading:15882171-Neoplasm Staging,
pubmed-meshheading:15882171-Retrospective Studies,
pubmed-meshheading:15882171-Risk Factors,
pubmed-meshheading:15882171-Treatment Outcome,
pubmed-meshheading:15882171-Uterine Cervical Neoplasms
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pubmed:articleTitle |
Effect of radiotherapy on pelvic lymph node metastasis in cervical cancer stages IB2-IVA: a retrospective analysis of two comparative series.
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pubmed:affiliation |
Fédération Femme-Mère-Nouveau-né, Hôpital Edouard Herriot Pavillon L, Lyon, France. daniel.dargent@wanadoo.fr
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pubmed:publicationType |
Journal Article,
Comparative Study
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