Linked Life Data

15881361

Source:http://linkedlifedata.com/resource/pubmed/id/15881361

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2005-5-9
pubmed:abstractText
A method based on capillary electrophoresis with end-column electrochemical detection (HPCE-ED) was developed for the determination of the diuretics of hydrochlorothiazide (HCT) and triamterene (TAT) simultaneously. The detection electrode was a 300 microm carbon disc electrode at a working potential of +1.1 V versus Ag/AgCl electrode. The two analytes could be well separated within 8 min in a 50 cm long capillary at a separation voltage of 24 kV with a 10 mmol/L phosphate buffer (pH 7.5). Under optimum conditions, the current response was linear over about two orders of magnitude with detection limits (S/N = 3) of 0.29 and 0.25 mg/L for triamterene and hydrochlorothiazide, respectively. The proposed method was successfully applied to determine the synthetic urine and real pharmaceuticals samples. The recoveries were found to be in the range of 93.5%-97.2%.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1000-8713
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
22-5
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
[Capillary electrophoresis with end-column electrochemical detection for hydrochlorothiazide and triamterene diuretics].
pubmed:affiliation
School of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350002, China. zlan@fzu.edu.cn
pubmed:publicationType
Journal Article, English Abstract