Source:http://linkedlifedata.com/resource/pubmed/id/15878272
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
|
pubmed:dateCreated |
2005-5-31
|
pubmed:abstractText |
A series of 2,4,6-trisubstituted-pyrimidines was synthesized and evaluated for their in vitro antimalarial activity against Plasmodium falciparum. Out of the 30 compounds synthesized 21 compounds showed MIC in the range of 0.5-2 microg/mL. These compounds are in vitro several folds more active than pyrimethamine.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0960-894X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3130-2
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15878272-Animals,
pubmed-meshheading:15878272-Antimalarials,
pubmed-meshheading:15878272-Microbial Sensitivity Tests,
pubmed-meshheading:15878272-Plasmodium falciparum,
pubmed-meshheading:15878272-Pyrimethamine,
pubmed-meshheading:15878272-Pyrimidines,
pubmed-meshheading:15878272-Structure-Activity Relationship
|
pubmed:year |
2005
|
pubmed:articleTitle |
Antimalarial activity and synthesis of new trisubstituted pyrimidines.
|
pubmed:affiliation |
Division of Medicinal and Process Chemistry, Central Drug Research Institute, Lucknow 226001, India.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|