|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0000768,
umls-concept:C0021641,
umls-concept:C0028754,
umls-concept:C0030274,
umls-concept:C0033607,
umls-concept:C0034693,
umls-concept:C0129975,
umls-concept:C0205462,
umls-concept:C0242339,
umls-concept:C0243067,
umls-concept:C1292733,
umls-concept:C1327616,
umls-concept:C1555029,
umls-concept:C1883254
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|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2005-5-6
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|
pubmed:abstractText |
Otsuka Long-Evans Tokushima Fatty (OLETF) rat, a model of type 2 diabetes, lacks the expression of cholecystokinin-1 receptor mRNA and exhibits inflammation and degeneration of the pancreas and eventually develops insulinopenic diabetes. Protease inhibitors are known to modulate inflammatory response and fibrosis as well as inhibit proteases activity.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
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pubmed:month |
May
|
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pubmed:issn |
0026-0495
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
54
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
|
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pubmed:pagination |
619-27
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|
pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15877292-Adipose Tissue,
pubmed-meshheading:15877292-Animals,
pubmed-meshheading:15877292-Blood Glucose,
pubmed-meshheading:15877292-Body Weight,
pubmed-meshheading:15877292-Diabetes Mellitus, Type 2,
pubmed-meshheading:15877292-Eating,
pubmed-meshheading:15877292-Fasting,
pubmed-meshheading:15877292-Gabexate,
pubmed-meshheading:15877292-Glucose Tolerance Test,
pubmed-meshheading:15877292-Hyperlipidemias,
pubmed-meshheading:15877292-Insulin,
pubmed-meshheading:15877292-Insulin Resistance,
pubmed-meshheading:15877292-Lipids,
pubmed-meshheading:15877292-Male,
pubmed-meshheading:15877292-Obesity,
pubmed-meshheading:15877292-Pancreas,
pubmed-meshheading:15877292-Protease Inhibitors,
pubmed-meshheading:15877292-Rats,
pubmed-meshheading:15877292-Rats, Inbred OLETF
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|
pubmed:year |
2005
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|
pubmed:articleTitle |
Synthetic protease inhibitor camostat prevents and reverses dyslipidemia, insulin secretory defects, and histological abnormalities of the pancreas in genetically obese and diabetic rats.
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|
pubmed:affiliation |
Third Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushu 807-8555, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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