Linked Life Data

15877075

Source:http://linkedlifedata.com/resource/pubmed/id/15877075

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2005-5-6
pubmed:abstractText
Today, many thousands of recombinant proteins, ranging from cytosolic enzymes to membrane-bound proteins, have been successfully produced in baculovirus-infected insect cells. Yet, in addition to its value in producing recombinant proteins in insect cells and larvae, this viral vector system continues to evolve in new and unexpected ways. This is exemplified by the development of engineered insect cell lines to mimic mammalian cell glycosylation of expressed proteins, baculovirus display strategies and the application of the virus as a mammalian-cell gene delivery vector. Novel vector design and cell engineering approaches will serve to further enhance the value of baculovirus technology.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1087-0156
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
567-75
pubmed:dateRevised
2011-8-1
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Baculovirus as versatile vectors for protein expression in insect and mammalian cells.
pubmed:affiliation
Gene Expression Protein Biochemistry, GlaxoSmithKline R&D, 5 Moore Drive, Research Triangle Park, North Carolina 27709, USA. tom.a.kost@gsk.com <tom.a.kost@gsk.com>
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Review, Research Support, N.I.H., Extramural