Linked Life Data

15872017

Source:http://linkedlifedata.com/resource/pubmed/id/15872017

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
Pt 7
pubmed:dateCreated
2005-6-27
pubmed:abstractText
In an attempt to provide a common denominator for cognitive deficits observed in cerebellar patients, it has been suggested that they might be secondary to impaired control of attention, a 'dysmetria of attention', conceptually analogous to motor dysmetria. Albeit appealing and quite influential, the concept of attentional dysmetria as a consequence of cerebellar disease remains controversial. In an attempt to test this concept in a direct way, we compared the performance of patients with cerebellar disorders to that of normal controls on tasks requiring either overt or covert shifts of spatial attention. In the first experiment, visually guided saccades, i.e. overt shifts of spatial attention, were elicited. In the second experiment, covert shifts of attention were evoked by the need to discriminate the orientation of a Landolt C observed during controlled fixation and presented in the same locations as the saccade targets in the previous experiment. The allocation of attention was assessed by comparing acuity thresholds determined with and without spatial cueing. The patients exhibited dysmetric saccades as reflected by larger absolute position errors or a higher number of corrective saccades compared to controls. In contrast, the ability to shift attention covertly was unimpaired in the patients, as indicated by a robust improvement in visual acuity induced by spatial cueing which did not differ from the one observed in the controls and which was independent of the range of SOAs (stimulus onset asynchronies) tested. Finally, the individual amount of saccadic dysmetria did not correlate with the individual performance in the covert attentional paradigm. In summary, we conclude that the contributions of the cerebellum to attention are confined to overt manifestations based on goal-directed eye movements.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1460-2156
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
128
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1525-35
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Disturbed overt but normal covert shifts of attention in adult cerebellar patients.
pubmed:affiliation
Department of Cognitive Neurology, Hertie-Institute for Clinical Brain Research, University of Tübingen, Klinikum Schnarrenberg, Tübingen, Germany. heidrun.golla@uni-tuebingen.de
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't