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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2005-5-3
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pubmed:abstractText |
The serine protease stratum corneum chymotryptic enzyme (SCCE) is overexpressed by ovarian tumor cells, but is not expressed by normal tissues, suggesting that SCCE may be an attractive target for immunotherapy. In this study, we tested the hypothesis that dendritic cells loaded with SCCE peptides will induce ovarian tumor antigen-specific CD8+ CTL responses and antigen-specific CD4+ helper T cell responses.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/HLA-A2 Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Immunodominant Epitopes,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-4,
http://linkedlifedata.com/resource/pubmed/chemical/KLK7 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Kallikreins,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Fragments,
http://linkedlifedata.com/resource/pubmed/chemical/Serine Endopeptidases
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3446-54
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15867247-Amino Acid Sequence,
pubmed-meshheading:15867247-Antigens, Neoplasm,
pubmed-meshheading:15867247-CD4-Positive T-Lymphocytes,
pubmed-meshheading:15867247-CD8-Positive T-Lymphocytes,
pubmed-meshheading:15867247-Cell Line, Tumor,
pubmed-meshheading:15867247-Cytotoxicity, Immunologic,
pubmed-meshheading:15867247-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:15867247-Dendritic Cells,
pubmed-meshheading:15867247-Female,
pubmed-meshheading:15867247-HLA-A2 Antigen,
pubmed-meshheading:15867247-Humans,
pubmed-meshheading:15867247-Immunodominant Epitopes,
pubmed-meshheading:15867247-Interferon-gamma,
pubmed-meshheading:15867247-Interleukin-4,
pubmed-meshheading:15867247-K562 Cells,
pubmed-meshheading:15867247-Kallikreins,
pubmed-meshheading:15867247-Molecular Sequence Data,
pubmed-meshheading:15867247-Ovarian Neoplasms,
pubmed-meshheading:15867247-Peptide Fragments,
pubmed-meshheading:15867247-Protein Binding,
pubmed-meshheading:15867247-Serine Endopeptidases,
pubmed-meshheading:15867247-T-Lymphocytes, Cytotoxic
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pubmed:year |
2005
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pubmed:articleTitle |
Definition of an immunogenic region within the ovarian tumor antigen stratum corneum chymotryptic enzyme.
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pubmed:affiliation |
Department of Microbiology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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