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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2005-5-3
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pubmed:abstractText |
YKL-40 is a secreted protein that has been reported to be overexpressed in epithelial cancers and gliomas, although its function is unknown. Previous data in a smaller sample set suggested that YKL-40 was a marker associated with a poorer clinical outcome and a genetically defined subgroup of glioblastoma. Here we test these findings in a larger series of patients with glioblastoma, and in particular, determine if tumor YKL-40 expression is associated with radiation response.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:AldapeKenneth DKD,
pubmed-author:BlairHilaryH,
pubmed-author:ChangEric LEL,
pubmed-author:ColmanHowardH,
pubmed-author:GilbertMarkM,
pubmed-author:JenkinsRobert BRB,
pubmed-author:LedouxAliciaA,
pubmed-author:MahajanAnitaA,
pubmed-author:MaorMosheM,
pubmed-author:PasseSandraS,
pubmed-author:PelloskiChristopher ECE,
pubmed-author:WooShiaoS,
pubmed-author:YangHelenH
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3326-34
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15867231-Adipokines,
pubmed-meshheading:15867231-Adult,
pubmed-meshheading:15867231-Aged,
pubmed-meshheading:15867231-Brain,
pubmed-meshheading:15867231-Brain Neoplasms,
pubmed-meshheading:15867231-Chromosome Aberrations,
pubmed-meshheading:15867231-Chromosomes, Human, Pair 10,
pubmed-meshheading:15867231-Combined Modality Therapy,
pubmed-meshheading:15867231-Female,
pubmed-meshheading:15867231-Gene Amplification,
pubmed-meshheading:15867231-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:15867231-Glioblastoma,
pubmed-meshheading:15867231-Glycoproteins,
pubmed-meshheading:15867231-Humans,
pubmed-meshheading:15867231-Immunohistochemistry,
pubmed-meshheading:15867231-In Situ Hybridization, Fluorescence,
pubmed-meshheading:15867231-Lectins,
pubmed-meshheading:15867231-Magnetic Resonance Imaging,
pubmed-meshheading:15867231-Male,
pubmed-meshheading:15867231-Middle Aged,
pubmed-meshheading:15867231-Multivariate Analysis,
pubmed-meshheading:15867231-Prognosis,
pubmed-meshheading:15867231-Receptor, Epidermal Growth Factor,
pubmed-meshheading:15867231-Survival Analysis,
pubmed-meshheading:15867231-Treatment Outcome
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pubmed:year |
2005
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pubmed:articleTitle |
YKL-40 expression is associated with poorer response to radiation and shorter overall survival in glioblastoma.
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pubmed:affiliation |
Department of Radiation Oncology, Neuro-Oncology, and Pathology, University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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