| pubmed-article:15866482 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15866482 | lifeskim:mentions | umls-concept:C0023779 | lld:lifeskim |
| pubmed-article:15866482 | lifeskim:mentions | umls-concept:C0014139 | lld:lifeskim |
| pubmed-article:15866482 | lifeskim:mentions | umls-concept:C1413218 | lld:lifeskim |
| pubmed-article:15866482 | lifeskim:mentions | umls-concept:C0243144 | lld:lifeskim |
| pubmed-article:15866482 | lifeskim:mentions | umls-concept:C1611645 | lld:lifeskim |
| pubmed-article:15866482 | lifeskim:mentions | umls-concept:C0127400 | lld:lifeskim |
| pubmed-article:15866482 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:15866482 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:15866482 | pubmed:dateCreated | 2005-5-3 | lld:pubmed |
| pubmed-article:15866482 | pubmed:abstractText | The scavenger receptor class B, type I (SR-BI) mediates the cellular selective uptake of cholesteryl esters and other lipids from high-density lipoproteins (HDL) and low-density lipoproteins (LDL). This process, unlike classical receptor-mediated endocytosis, does not result in lipoprotein degradation. Instead, the lipid depleted particles are released into the medium. Here we show that selective lipid uptake mediated by murine SR-BI can be uncoupled from the endocytosis of HDL or LDL particles. We found that blocking selective lipid uptake by incubating cells with the small chemical inhibitors BLT-1 or BLT-4 did not affect endocytosis of HDL. Similarly, blocking endocytosis by hyperosmotic sucrose or K+ depletion did not prevent selective lipid uptake from HDL or LDL. These findings suggest that mSR-BI-mediated selective uptake occurs at the cell surface upon the association of lipoproteins with mSR-BI and does not require endocytosis of HDL or LDL particles. | lld:pubmed |
| pubmed-article:15866482 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15866482 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15866482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15866482 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15866482 | pubmed:month | May | lld:pubmed |
| pubmed-article:15866482 | pubmed:issn | 0006-3002 | lld:pubmed |
| pubmed-article:15866482 | pubmed:author | pubmed-author:EhrlichMarcel... | lld:pubmed |
| pubmed-article:15866482 | pubmed:author | pubmed-author:KriegerMontyM | lld:pubmed |
| pubmed-article:15866482 | pubmed:author | pubmed-author:KirchhausenTo... | lld:pubmed |
| pubmed-article:15866482 | pubmed:author | pubmed-author:NielandThomas... | lld:pubmed |
| pubmed-article:15866482 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15866482 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:15866482 | pubmed:volume | 1734 | lld:pubmed |
| pubmed-article:15866482 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15866482 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15866482 | pubmed:pagination | 44-51 | lld:pubmed |
| pubmed-article:15866482 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:meshHeading | pubmed-meshheading:15866482... | lld:pubmed |
| pubmed-article:15866482 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15866482 | pubmed:articleTitle | Endocytosis is not required for the selective lipid uptake mediated by murine SR-BI. | lld:pubmed |
| pubmed-article:15866482 | pubmed:affiliation | Department of Cell Biology, Harvard Medical School and The CBR Institute for Biomedical Research, 200 Longwood Avenue, Room 134, Boston, MA 02115, USA. | lld:pubmed |
| pubmed-article:15866482 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15866482 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:15866482 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| entrez-gene:20778 | entrezgene:pubmed | pubmed-article:15866482 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15866482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15866482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15866482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15866482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15866482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15866482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15866482 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15866482 | lld:pubmed |
