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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1992-6-22
|
| pubmed:abstractText |
The purpose of this study is to describe the incidence and survival of childhood cancer in the West Midlands for the period 1980-1984. Proportional breakdown by Asian subgroup is also considered. A total of 587 patients were registered, 49 of them of Asian origin. Breakdown to Asian versus non-Asian subgroups by diagnosis revealed comparatively high rates for Hodgkin's disease, retinoblastoma and neuroblastoma in the Asian patients. However, a deficit of cases was seen for CNS tumours. Comparison of overall age-standardized rates (ASR) for all cancers revealed a substantially lower value compared to that reported for the USA white population but a similar value to the USA black and UK white populations. Diagnostic breakdown revealed that the major difference between the West Midlands Regional Children's Tumour Research Group (WMRCTRG) and the USA white ASR was in the leukaemia and lymphoma group. Overall survival for the series was 56% at 5 years. The poorest prognosis was found in acute myeloid leukaemia, with only 23% of patients surviving at 5 years, against 62% in acute lymphoblastic leukaemia. CNS tumours also had a poor outcome, with an overall survival rate of 47%, although certain individual diagnoses were more favourable. We observed a 100% survival rate in Hodgkin's disease up to 5 years from diagnosis, and both Wilms' tumour and retinoblastoma had 90% survival rates.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0936-6555
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
4
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
177-82
|
| pubmed:dateRevised |
2008-3-10
|
| pubmed:meshHeading |
pubmed-meshheading:1586636-Adolescent,
pubmed-meshheading:1586636-Asia,
pubmed-meshheading:1586636-Asian Continental Ancestry Group,
pubmed-meshheading:1586636-Central Nervous System Neoplasms,
pubmed-meshheading:1586636-Child,
pubmed-meshheading:1586636-Child, Preschool,
pubmed-meshheading:1586636-England,
pubmed-meshheading:1586636-Ethnic Groups,
pubmed-meshheading:1586636-Female,
pubmed-meshheading:1586636-Hodgkin Disease,
pubmed-meshheading:1586636-Humans,
pubmed-meshheading:1586636-Incidence,
pubmed-meshheading:1586636-Infant,
pubmed-meshheading:1586636-Leukemia,
pubmed-meshheading:1586636-Male,
pubmed-meshheading:1586636-Neoplasms,
pubmed-meshheading:1586636-Neuroblastoma,
pubmed-meshheading:1586636-Registries,
pubmed-meshheading:1586636-Retinoblastoma,
pubmed-meshheading:1586636-Survival Rate,
pubmed-meshheading:1586636-Wales
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
Childhood cancer in the West Midlands: incidence and survival, 1980-1984, in a multi-ethnic population.
|
| pubmed:affiliation |
West Midlands Regional Children's Tumour Research Group, Children's Hospital, Birmingham, UK.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|