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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1992-6-18
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pubmed:abstractText |
Thromboembolic complications in beta-thalassemia major have seldom been reported and their association with risk factors such as left ventricular failure and postsplenectomy thrombocytosis has remained speculative. In this report we describe 4 patients with unusual thromboembolic manifestations: recurrent arterial occlusion, recurrent pulmonary thromboembolism, venous thrombosis and a fatal cerebrovascular event. Although in all patients both risk factors were present, the precise causes for their thromboembolic complications were not identified. In 1 patient, however, a marked increase in hematocrit following blood transfusion resulted, in all likelihood, in a fatal cerebrovascular infarction. We suspect that these patients (constituting 4% of our beta-thalassemic group) represent a subset of those with high susceptibility to both arterial and venous thromboembolic complications.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
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pubmed:issn |
0001-5792
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
71-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1585774-Adolescent,
pubmed-meshheading:1585774-Adult,
pubmed-meshheading:1585774-Arterial Occlusive Diseases,
pubmed-meshheading:1585774-Cerebrovascular Disorders,
pubmed-meshheading:1585774-Electrocardiography,
pubmed-meshheading:1585774-Female,
pubmed-meshheading:1585774-Humans,
pubmed-meshheading:1585774-Male,
pubmed-meshheading:1585774-Pulmonary Embolism,
pubmed-meshheading:1585774-Thalassemia,
pubmed-meshheading:1585774-Thromboembolism,
pubmed-meshheading:1585774-Thrombophlebitis
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pubmed:year |
1992
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pubmed:articleTitle |
Thromboembolic complications in beta thalassemia major.
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pubmed:affiliation |
Department of Hematology, Hadassah University Hospital, Jerusalem, Israel.
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pubmed:publicationType |
Journal Article,
Case Reports
|