Linked Life Data

15857182

Source:http://linkedlifedata.com/resource/pubmed/id/15857182

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2005-4-28
pubmed:abstractText
The 35delG mutation in the connexin 26 gene (GJB2) at the DFNB1 locus represents the most common mutation in Caucasian patients with genetic sensorineural deafness. This new meta-analysis concerns published carrier frequencies of the 35delG mutation in 27 populations for 6,628 unrelated individuals in Europe and in the Middle East; the mean carrier frequency of the mutation is 1.9%. Compared on a regional basis, the most elevated carrier frequency value is of 1 individual carrier in 31 in southern Europe. It is probable that the 35delG mutation originated in ancient Greece and was subsequently propagated in other Mediterranean countries (especially in Italy) during recent historical times.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1090-6576
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
20-5
pubmed:dateRevised
2006-3-28
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
The 35delG mutation in the connexin 26 gene (GJB2) associated with congenital deafness: European carrier frequencies and evidence for its origin in ancient Greece.
pubmed:affiliation
Institute of Molecular Anthropology, 75005 Paris, France. lucotte@hotmail.com
pubmed:publicationType
Journal Article